Listen to Patient’s Gut: A Case Report of a Woman With Fatigue and Bruising
A 65-year-old female patient with dermatomyositis and lipodystrophy presented with fatigue and severe anemia. Abdominal auscultation revealed a loud hum in the epigastrium, consistent with a Cruveilhier-Baumgarten murmur, typically associated with portal hypertension. Magnetic resonance imaging show...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-01-01
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| Series: | Gastro Hep Advances |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772572325001013 |
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| author | Maria Mironova Nadera Altork Harish Gopalakrishna David E. Kleiner Theo Heller |
| author_facet | Maria Mironova Nadera Altork Harish Gopalakrishna David E. Kleiner Theo Heller |
| author_sort | Maria Mironova |
| collection | DOAJ |
| description | A 65-year-old female patient with dermatomyositis and lipodystrophy presented with fatigue and severe anemia. Abdominal auscultation revealed a loud hum in the epigastrium, consistent with a Cruveilhier-Baumgarten murmur, typically associated with portal hypertension. Magnetic resonance imaging showed signs of portal hypertension, including recanalization of paraumbilical vein. Liver biopsy demonstrated sinusoidal dilation without cirrhosis, leading to a diagnosis of portosinusoidal vascular disease. Upper endoscopy confirmed portal hypertensive gastropathy as the cause of anemia. This case highlights the importance of a thorough physical examination in guiding subsequent imaging and diagnostic workup. |
| format | Article |
| id | doaj-art-32273dfda28e45029ab2ff4e92f6bcda |
| institution | DOAJ |
| issn | 2772-5723 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Gastro Hep Advances |
| spelling | doaj-art-32273dfda28e45029ab2ff4e92f6bcda2025-08-20T02:46:25ZengElsevierGastro Hep Advances2772-57232025-01-014910071410.1016/j.gastha.2025.100714Listen to Patient’s Gut: A Case Report of a Woman With Fatigue and BruisingMaria Mironova0Nadera Altork1Harish Gopalakrishna2David E. Kleiner3Theo Heller4Translational Hepatology Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MarylandMedStar Health/Georgetown-Washington Hospital Center, Washington, District of ColumbiaTranslational Hepatology Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MarylandLaboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, MarylandTranslational Hepatology Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland; Correspondence: Address correspondence to: Theo Heller, MD, Translational Hepatology Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 10 Center Drive, Building 10, Room 4-5722, Bethesda, MD 20892.A 65-year-old female patient with dermatomyositis and lipodystrophy presented with fatigue and severe anemia. Abdominal auscultation revealed a loud hum in the epigastrium, consistent with a Cruveilhier-Baumgarten murmur, typically associated with portal hypertension. Magnetic resonance imaging showed signs of portal hypertension, including recanalization of paraumbilical vein. Liver biopsy demonstrated sinusoidal dilation without cirrhosis, leading to a diagnosis of portosinusoidal vascular disease. Upper endoscopy confirmed portal hypertensive gastropathy as the cause of anemia. This case highlights the importance of a thorough physical examination in guiding subsequent imaging and diagnostic workup.http://www.sciencedirect.com/science/article/pii/S2772572325001013AusculationPortal hypertensionCirrhosisLiver transplant |
| spellingShingle | Maria Mironova Nadera Altork Harish Gopalakrishna David E. Kleiner Theo Heller Listen to Patient’s Gut: A Case Report of a Woman With Fatigue and Bruising Gastro Hep Advances Ausculation Portal hypertension Cirrhosis Liver transplant |
| title | Listen to Patient’s Gut: A Case Report of a Woman With Fatigue and Bruising |
| title_full | Listen to Patient’s Gut: A Case Report of a Woman With Fatigue and Bruising |
| title_fullStr | Listen to Patient’s Gut: A Case Report of a Woman With Fatigue and Bruising |
| title_full_unstemmed | Listen to Patient’s Gut: A Case Report of a Woman With Fatigue and Bruising |
| title_short | Listen to Patient’s Gut: A Case Report of a Woman With Fatigue and Bruising |
| title_sort | listen to patient s gut a case report of a woman with fatigue and bruising |
| topic | Ausculation Portal hypertension Cirrhosis Liver transplant |
| url | http://www.sciencedirect.com/science/article/pii/S2772572325001013 |
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