Spontaneous Complete Remission in a Patient with Acute Myeloid Leukemia and Severe Sepsis

Without treatment, acute myeloid leukemia (AML) is almost always fatal. Spontaneous remission of AML is a rare phenomenon and usually with a short duration. The exact mechanisms are unknown. However, its association with infection and blood transfusions has been described. We report a 53-year-old ma...

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Main Authors: Rambod Mozafari, Mahsa Moeinian, Ali Asadollahi-Amin
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Case Reports in Hematology
Online Access:http://dx.doi.org/10.1155/2017/9593750
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author Rambod Mozafari
Mahsa Moeinian
Ali Asadollahi-Amin
author_facet Rambod Mozafari
Mahsa Moeinian
Ali Asadollahi-Amin
author_sort Rambod Mozafari
collection DOAJ
description Without treatment, acute myeloid leukemia (AML) is almost always fatal. Spontaneous remission of AML is a rare phenomenon and usually with a short duration. The exact mechanisms are unknown. However, its association with infection and blood transfusions has been described. We report a 53-year-old male who presented with severe sepsis and who was diagnosed with AML (M4). He has experienced complete spontaneous remission with relatively long duration. To the best of our knowledge, it is the first case of spontaneous remission described in Iran.
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institution Kabale University
issn 2090-6560
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publishDate 2017-01-01
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series Case Reports in Hematology
spelling doaj-art-321d2b73ccad448396b2db85a912072a2025-02-03T07:24:52ZengWileyCase Reports in Hematology2090-65602090-65792017-01-01201710.1155/2017/95937509593750Spontaneous Complete Remission in a Patient with Acute Myeloid Leukemia and Severe SepsisRambod Mozafari0Mahsa Moeinian1Ali Asadollahi-Amin2Department of Hematology, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, IranResearch Center for Rational Use of Drugs, Tehran University of Medical Sciences, Tehran, IranDepartment of Infectious Disease, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, IranWithout treatment, acute myeloid leukemia (AML) is almost always fatal. Spontaneous remission of AML is a rare phenomenon and usually with a short duration. The exact mechanisms are unknown. However, its association with infection and blood transfusions has been described. We report a 53-year-old male who presented with severe sepsis and who was diagnosed with AML (M4). He has experienced complete spontaneous remission with relatively long duration. To the best of our knowledge, it is the first case of spontaneous remission described in Iran.http://dx.doi.org/10.1155/2017/9593750
spellingShingle Rambod Mozafari
Mahsa Moeinian
Ali Asadollahi-Amin
Spontaneous Complete Remission in a Patient with Acute Myeloid Leukemia and Severe Sepsis
Case Reports in Hematology
title Spontaneous Complete Remission in a Patient with Acute Myeloid Leukemia and Severe Sepsis
title_full Spontaneous Complete Remission in a Patient with Acute Myeloid Leukemia and Severe Sepsis
title_fullStr Spontaneous Complete Remission in a Patient with Acute Myeloid Leukemia and Severe Sepsis
title_full_unstemmed Spontaneous Complete Remission in a Patient with Acute Myeloid Leukemia and Severe Sepsis
title_short Spontaneous Complete Remission in a Patient with Acute Myeloid Leukemia and Severe Sepsis
title_sort spontaneous complete remission in a patient with acute myeloid leukemia and severe sepsis
url http://dx.doi.org/10.1155/2017/9593750
work_keys_str_mv AT rambodmozafari spontaneouscompleteremissioninapatientwithacutemyeloidleukemiaandseveresepsis
AT mahsamoeinian spontaneouscompleteremissioninapatientwithacutemyeloidleukemiaandseveresepsis
AT aliasadollahiamin spontaneouscompleteremissioninapatientwithacutemyeloidleukemiaandseveresepsis