GGCX promotes Eurasian avian-like H1N1 swine influenza virus adaption to interspecies receptor binding

GGCX promotes Eurasian avian-like H1N1 swine influenza virus adaption to interspecies receptor binding

Abstract The Eurasian avian-like (EA) H1N1 swine influenza virus (SIV) possesses the capacity to instigate the next influenza pandemic, owing to its heightened affinity for the human-type α-2,6 sialic acid (SA) receptor. Nevertheless, the molecular mechanisms underlying the switch in receptor bindin...

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Main Authors: Jiahui Zou, Meijun Jiang, Rong Xiao, Huimin Sun, Hailong Liu, Thomas Peacock, Shaoyu Tu, Tong Chen, Jinli Guo, Yaxin Zhao, Wendy Barclay, Shengsong Xie, Hongbo Zhou
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-55903-0
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