Congenital toxoplasmosis in infants from chronically infected mothers: report of two cases
ABSTRACT Objective: To describe two severe cases of congenital toxoplasmosis in infants born to chronically infected mothers who did not receive education or information on the prevention of gestational toxoplasmosis during prenatal care. Case description: The mothers had a previous serological di...
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Sociedade de Pediatria de São Paulo
2025-01-01
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| Series: | Revista Paulista de Pediatria |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-05822025000100605&lng=en&tlng=en |
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| author | Roberta Rassi Almeida Geovana Batista de Campos Ana Maria Castro |
| author_facet | Roberta Rassi Almeida Geovana Batista de Campos Ana Maria Castro |
| author_sort | Roberta Rassi Almeida |
| collection | DOAJ |
| description | ABSTRACT Objective: To describe two severe cases of congenital toxoplasmosis in infants born to chronically infected mothers who did not receive education or information on the prevention of gestational toxoplasmosis during prenatal care. Case description: The mothers had a previous serological diagnosis of toxoplasmosis conducted during prenatal care, with non-reactive (<10 IU/mL) IgM and reactive IgG (>10 IU/mL), and were considered “immune” to the infection. Both infants were born with sequelae of the congenital infection, including neurological and ocular alterations. Comments: Managing gestational toxoplasmosis in susceptible pregnant women is a considerable challenge in several countries, especially in South America. It is necessary to diagnose and monitor chronic gestational toxoplasmosis, as it may result from reactivation or reinfection. Both forms can cause sequelae and irreparable damage to newborns. In addition, it is essential to guide all pregnant women on how to avoid contact with Toxoplasma gondii, regardless of their serological status. |
| format | Article |
| id | doaj-art-31d72f2bb0844076a363582f82e3cece |
| institution | Kabale University |
| issn | 1984-0462 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Sociedade de Pediatria de São Paulo |
| record_format | Article |
| series | Revista Paulista de Pediatria |
| spelling | doaj-art-31d72f2bb0844076a363582f82e3cece2025-01-21T07:41:18ZengSociedade de Pediatria de São PauloRevista Paulista de Pediatria1984-04622025-01-014310.1590/1984-0462/2025/43/2024120Congenital toxoplasmosis in infants from chronically infected mothers: report of two casesRoberta Rassi Almeidahttps://orcid.org/0009-0007-0400-4147Geovana Batista de Camposhttps://orcid.org/0000-0002-4577-6748Ana Maria Castrohttps://orcid.org/0000-0003-3327-967XABSTRACT Objective: To describe two severe cases of congenital toxoplasmosis in infants born to chronically infected mothers who did not receive education or information on the prevention of gestational toxoplasmosis during prenatal care. Case description: The mothers had a previous serological diagnosis of toxoplasmosis conducted during prenatal care, with non-reactive (<10 IU/mL) IgM and reactive IgG (>10 IU/mL), and were considered “immune” to the infection. Both infants were born with sequelae of the congenital infection, including neurological and ocular alterations. Comments: Managing gestational toxoplasmosis in susceptible pregnant women is a considerable challenge in several countries, especially in South America. It is necessary to diagnose and monitor chronic gestational toxoplasmosis, as it may result from reactivation or reinfection. Both forms can cause sequelae and irreparable damage to newborns. In addition, it is essential to guide all pregnant women on how to avoid contact with Toxoplasma gondii, regardless of their serological status.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-05822025000100605&lng=en&tlng=enChildCongenital toxoplasmosisChronic infectionNeglected diseasesCase report |
| spellingShingle | Roberta Rassi Almeida Geovana Batista de Campos Ana Maria Castro Congenital toxoplasmosis in infants from chronically infected mothers: report of two cases Revista Paulista de Pediatria Child Congenital toxoplasmosis Chronic infection Neglected diseases Case report |
| title | Congenital toxoplasmosis in infants from chronically infected mothers: report of two cases |
| title_full | Congenital toxoplasmosis in infants from chronically infected mothers: report of two cases |
| title_fullStr | Congenital toxoplasmosis in infants from chronically infected mothers: report of two cases |
| title_full_unstemmed | Congenital toxoplasmosis in infants from chronically infected mothers: report of two cases |
| title_short | Congenital toxoplasmosis in infants from chronically infected mothers: report of two cases |
| title_sort | congenital toxoplasmosis in infants from chronically infected mothers report of two cases |
| topic | Child Congenital toxoplasmosis Chronic infection Neglected diseases Case report |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-05822025000100605&lng=en&tlng=en |
| work_keys_str_mv | AT robertarassialmeida congenitaltoxoplasmosisininfantsfromchronicallyinfectedmothersreportoftwocases AT geovanabatistadecampos congenitaltoxoplasmosisininfantsfromchronicallyinfectedmothersreportoftwocases AT anamariacastro congenitaltoxoplasmosisininfantsfromchronicallyinfectedmothersreportoftwocases |