Folic Acid and Birth Defects: A Case Study (Iran)
The aim of this study was to evaluate the impact of folic acid use in pregnancy for the reduction of neural tube defects (NTDs) in the northwest region of Iran. We studied 243 women with pregnancies complicated by some forms of birth defect(s). These patients were identified by medical diagnostic te...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Journal of Pregnancy |
| Online Access: | http://dx.doi.org/10.1155/2011/370458 |
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| author | Mohammad Bager Hosseini Zhila Khamnian Saeed Dastgiri Bahram Samadi Raad Yalda Ravanshad |
| author_facet | Mohammad Bager Hosseini Zhila Khamnian Saeed Dastgiri Bahram Samadi Raad Yalda Ravanshad |
| author_sort | Mohammad Bager Hosseini |
| collection | DOAJ |
| description | The aim of this study was to evaluate the impact of folic acid use in pregnancy for the reduction of neural tube defects (NTDs) in the northwest region of Iran. We studied 243 women with pregnancies complicated by some forms of birth defect(s). These patients were identified by medical diagnostic tests as having a fetus with some types of congenital anomalies. The prevalence of NTDs among pregnant women who were referred for therapeutic termination of pregnancy was 24.7 percent. Consumption of folic acid prevented NTDs by 79 percent (Odds Ratio = 0.21, CI 95%: 0.12–0.40) and 94 percent (Odds Ratio = 0.06, CI 95%: 0.03–0.15) compared to pregnancies complicated by other anomalies and normal pregnancies, respectively. Hydrops fetalis, hydrocephaly, Down syndrome, and limb anomalies did not have any significant association with the folic acid use. Along with the advice for the consumption of folic acid for pregnant women, they should be offered prenatal screening or diagnostic tests to identify fetal abnormalities for possible termination of pregnancy. |
| format | Article |
| id | doaj-art-31b4d2f37cc24226ae11a0b05d0ef73a |
| institution | Kabale University |
| issn | 2090-2727 2090-2735 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Pregnancy |
| spelling | doaj-art-31b4d2f37cc24226ae11a0b05d0ef73a2025-02-03T01:32:16ZengWileyJournal of Pregnancy2090-27272090-27352011-01-01201110.1155/2011/370458370458Folic Acid and Birth Defects: A Case Study (Iran)Mohammad Bager Hosseini0Zhila Khamnian1Saeed Dastgiri2Bahram Samadi Raad3Yalda Ravanshad4Department of Neonatology, Children Health Research Centre, Tabriz University of Medical Sciences, Tabriz 515665931, IranDepartment of Community Medicine, National Public Health Management Centre (NPMC), School of Medicine, Tabriz University of Medical Sciences, Tabriz 515665931, IranDepartment of Community Medicine, National Public Health Management Centre (NPMC), School of Medicine, Tabriz University of Medical Sciences, Tabriz 515665931, IranDepartment of Forensic Medicine, Tabriz University of Medical Sciences, Tabriz 515665931, IranDepartment of Community Medicine, National Public Health Management Centre (NPMC), School of Medicine, Tabriz University of Medical Sciences, Tabriz 515665931, IranThe aim of this study was to evaluate the impact of folic acid use in pregnancy for the reduction of neural tube defects (NTDs) in the northwest region of Iran. We studied 243 women with pregnancies complicated by some forms of birth defect(s). These patients were identified by medical diagnostic tests as having a fetus with some types of congenital anomalies. The prevalence of NTDs among pregnant women who were referred for therapeutic termination of pregnancy was 24.7 percent. Consumption of folic acid prevented NTDs by 79 percent (Odds Ratio = 0.21, CI 95%: 0.12–0.40) and 94 percent (Odds Ratio = 0.06, CI 95%: 0.03–0.15) compared to pregnancies complicated by other anomalies and normal pregnancies, respectively. Hydrops fetalis, hydrocephaly, Down syndrome, and limb anomalies did not have any significant association with the folic acid use. Along with the advice for the consumption of folic acid for pregnant women, they should be offered prenatal screening or diagnostic tests to identify fetal abnormalities for possible termination of pregnancy.http://dx.doi.org/10.1155/2011/370458 |
| spellingShingle | Mohammad Bager Hosseini Zhila Khamnian Saeed Dastgiri Bahram Samadi Raad Yalda Ravanshad Folic Acid and Birth Defects: A Case Study (Iran) Journal of Pregnancy |
| title | Folic Acid and Birth Defects: A Case Study (Iran) |
| title_full | Folic Acid and Birth Defects: A Case Study (Iran) |
| title_fullStr | Folic Acid and Birth Defects: A Case Study (Iran) |
| title_full_unstemmed | Folic Acid and Birth Defects: A Case Study (Iran) |
| title_short | Folic Acid and Birth Defects: A Case Study (Iran) |
| title_sort | folic acid and birth defects a case study iran |
| url | http://dx.doi.org/10.1155/2011/370458 |
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