Decreased Cognitive/CNS Function in Young Adults at Risk for Hypertension: Effects of Sleep Deprivation
Hypertension has been linked to impaired cognitive/CNS function, and some of these changes may precede development of frank essential hypertension. The stress and fatigue of sleep deprivation may exacerbate these cognitive changes in young adults at risk. We hypothesize that individuals at risk for...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | International Journal of Hypertension |
| Online Access: | http://dx.doi.org/10.1155/2012/989345 |
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| author | James A. McCubbin Hannah Peach DeWayne D. Moore June J. Pilcher |
| author_facet | James A. McCubbin Hannah Peach DeWayne D. Moore June J. Pilcher |
| author_sort | James A. McCubbin |
| collection | DOAJ |
| description | Hypertension has been linked to impaired cognitive/CNS function, and some of these changes may precede development of frank essential hypertension. The stress and fatigue of sleep deprivation may exacerbate these cognitive changes in young adults at risk. We hypothesize that individuals at risk for hypertension will show significant declines in cognitive function during a night of sleep deprivation. Fifty-one young adults were recruited for 28-hour total sleep deprivation studies. Hypertension risk was assessed by mildly elevated resting blood pressure and by family history of hypertension. A series of cognitive memory tasks was given at four test sessions across the sleep deprivation period. Although initially comparable in cognitive performance, persons at risk showed larger declines across the night for several indices of working memory, including code substitution, category, and order recall. These results suggest that cognitive/CNS changes may parallel or precede blood pressure dysregulation in the early stages of hypertension development. The role of CNS changes in the etiology of essential hypertension is discussed. |
| format | Article |
| id | doaj-art-31605e5db60241df80344550ad8afdd1 |
| institution | Kabale University |
| issn | 2090-0384 2090-0392 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Hypertension |
| spelling | doaj-art-31605e5db60241df80344550ad8afdd12025-02-03T05:44:14ZengWileyInternational Journal of Hypertension2090-03842090-03922012-01-01201210.1155/2012/989345989345Decreased Cognitive/CNS Function in Young Adults at Risk for Hypertension: Effects of Sleep DeprivationJames A. McCubbin0Hannah Peach1DeWayne D. Moore2June J. Pilcher3Department of Psychology, Clemson University, Clemson, SC 29634, USADepartment of Psychology, Clemson University, Clemson, SC 29634, USADepartment of Psychology, Clemson University, Clemson, SC 29634, USADepartment of Psychology, Clemson University, Clemson, SC 29634, USAHypertension has been linked to impaired cognitive/CNS function, and some of these changes may precede development of frank essential hypertension. The stress and fatigue of sleep deprivation may exacerbate these cognitive changes in young adults at risk. We hypothesize that individuals at risk for hypertension will show significant declines in cognitive function during a night of sleep deprivation. Fifty-one young adults were recruited for 28-hour total sleep deprivation studies. Hypertension risk was assessed by mildly elevated resting blood pressure and by family history of hypertension. A series of cognitive memory tasks was given at four test sessions across the sleep deprivation period. Although initially comparable in cognitive performance, persons at risk showed larger declines across the night for several indices of working memory, including code substitution, category, and order recall. These results suggest that cognitive/CNS changes may parallel or precede blood pressure dysregulation in the early stages of hypertension development. The role of CNS changes in the etiology of essential hypertension is discussed.http://dx.doi.org/10.1155/2012/989345 |
| spellingShingle | James A. McCubbin Hannah Peach DeWayne D. Moore June J. Pilcher Decreased Cognitive/CNS Function in Young Adults at Risk for Hypertension: Effects of Sleep Deprivation International Journal of Hypertension |
| title | Decreased Cognitive/CNS Function in Young Adults at Risk for Hypertension: Effects of Sleep Deprivation |
| title_full | Decreased Cognitive/CNS Function in Young Adults at Risk for Hypertension: Effects of Sleep Deprivation |
| title_fullStr | Decreased Cognitive/CNS Function in Young Adults at Risk for Hypertension: Effects of Sleep Deprivation |
| title_full_unstemmed | Decreased Cognitive/CNS Function in Young Adults at Risk for Hypertension: Effects of Sleep Deprivation |
| title_short | Decreased Cognitive/CNS Function in Young Adults at Risk for Hypertension: Effects of Sleep Deprivation |
| title_sort | decreased cognitive cns function in young adults at risk for hypertension effects of sleep deprivation |
| url | http://dx.doi.org/10.1155/2012/989345 |
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