Cronkhite-Canada Syndrome: A Case Report and Review of Literature

Cronkhite-Canada syndrome (CCS) is a rare syndrome first described in 1955. (1) Since then, 400 cases worldwide have been reported in the literature. The disease is characterized by diffuse gastrointestinal polyposis, dystrophic changes of the fingernails, alopecia, cutaneous hyperpigmentation, diar...

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Main Authors: Kevin T. Kao, Jitesh K. Patel, Vijayamalini Pampati
Format: Article
Language:English
Published: Wiley 2009-01-01
Series:Gastroenterology Research and Practice
Online Access:http://dx.doi.org/10.1155/2009/619378
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author Kevin T. Kao
Jitesh K. Patel
Vijayamalini Pampati
author_facet Kevin T. Kao
Jitesh K. Patel
Vijayamalini Pampati
author_sort Kevin T. Kao
collection DOAJ
description Cronkhite-Canada syndrome (CCS) is a rare syndrome first described in 1955. (1) Since then, 400 cases worldwide have been reported in the literature. The disease is characterized by diffuse gastrointestinal polyposis, dystrophic changes of the fingernails, alopecia, cutaneous hyperpigmentation, diarrhea, weight loss, and abdominal pain. (2) The etiology is currently unknown, but an autoimmune process is suspected. The workup is based on history and physical followed by imaging and endoscopy with biopsy to confirm gastrointestinal polyposis. The goal of treatment focuses on symptomatic management of the patient and nutritional support.
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spelling doaj-art-30ecc1ce273747089ab5ae548063e0ed2025-02-03T01:10:52ZengWileyGastroenterology Research and Practice1687-61211687-630X2009-01-01200910.1155/2009/619378619378Cronkhite-Canada Syndrome: A Case Report and Review of LiteratureKevin T. Kao0Jitesh K. Patel1Vijayamalini Pampati2Department of Gastroenterology, Kaiser Permanente Los Angeles Medical Center, 1526 N. Edgemont Street, Los Angeles, CA 90027, USADepartment of Gastroenterology, Kaiser Permanente Woodland Hills Medical Center, 5601 De Soto Ave, Woodland Hills, CA 91367, USADepartment of Gastroenterology, Kaiser Permanente Los Angeles Medical Center, 1526 N. Edgemont Street, Los Angeles, CA 90027, USACronkhite-Canada syndrome (CCS) is a rare syndrome first described in 1955. (1) Since then, 400 cases worldwide have been reported in the literature. The disease is characterized by diffuse gastrointestinal polyposis, dystrophic changes of the fingernails, alopecia, cutaneous hyperpigmentation, diarrhea, weight loss, and abdominal pain. (2) The etiology is currently unknown, but an autoimmune process is suspected. The workup is based on history and physical followed by imaging and endoscopy with biopsy to confirm gastrointestinal polyposis. The goal of treatment focuses on symptomatic management of the patient and nutritional support.http://dx.doi.org/10.1155/2009/619378
spellingShingle Kevin T. Kao
Jitesh K. Patel
Vijayamalini Pampati
Cronkhite-Canada Syndrome: A Case Report and Review of Literature
Gastroenterology Research and Practice
title Cronkhite-Canada Syndrome: A Case Report and Review of Literature
title_full Cronkhite-Canada Syndrome: A Case Report and Review of Literature
title_fullStr Cronkhite-Canada Syndrome: A Case Report and Review of Literature
title_full_unstemmed Cronkhite-Canada Syndrome: A Case Report and Review of Literature
title_short Cronkhite-Canada Syndrome: A Case Report and Review of Literature
title_sort cronkhite canada syndrome a case report and review of literature
url http://dx.doi.org/10.1155/2009/619378
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