Backtranslation of human RNA biosignatures of tuberculosis disease risk into the preclinical pipeline is condition dependent
ABSTRACT It is unclear whether human progression to active tuberculosis disease (TB) risk signatures are viable endpoint criteria for evaluations of treatments in development. TB is the deadliest infectious disease globally and more efficacious vaccines are needed to reduce this mortality. However,...
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Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2025-01-01
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Series: | mSphere |
Subjects: | |
Online Access: | https://journals.asm.org/doi/10.1128/msphere.00864-24 |
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