Coexistence of Takayasu’s Arteritis in Patients with Inflammatory Bowel Diseases
Background. Takayasu’s arteritis (TA) and inflammatory bowel disease (IBD) are chronic inflammatory granulomatous disorders that have rarely been concomitantly reported in case reports and small case series. Objective. We report a series of seven cases of TA and IBD association in two referral cente...
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2021/8831867 |
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| author | Camilla de Almeida Martins Ana Elisa Rabe Caon Carolina Bortolozzo Graciolli Facanali Carlos Walter Sobrado Sergio Carlos Nahas Rosa Maria Rodrigues Pereira Reuma Margalit-Yehuda Uri Kopylov Natalia Sousa Freitas Queiroz |
| author_facet | Camilla de Almeida Martins Ana Elisa Rabe Caon Carolina Bortolozzo Graciolli Facanali Carlos Walter Sobrado Sergio Carlos Nahas Rosa Maria Rodrigues Pereira Reuma Margalit-Yehuda Uri Kopylov Natalia Sousa Freitas Queiroz |
| author_sort | Camilla de Almeida Martins |
| collection | DOAJ |
| description | Background. Takayasu’s arteritis (TA) and inflammatory bowel disease (IBD) are chronic inflammatory granulomatous disorders that have rarely been concomitantly reported in case reports and small case series. Objective. We report a series of seven cases of TA and IBD association in two referral centers with a comprehensive review of literature. Methods. We analyzed retrospectively the electronic medical charts of TA-IBD patients at the University Hospital of São Paulo, Brazil, and at the Sheba Medical Center at Tel Aviv University, Israel. Results. Overall, five patients had Crohn’s disease (DC) and two had ulcerative colitis (UC), and they were mostly female and non-Asian. All patients developed IBD first and, subsequently, TA. Two underwent colectomy and one ileocecectomy due to IBD activity, while three required cardiovascular surgery due to TA activity. Most patients are currently in clinical remission of both diseases with conventional drug treatment. Conclusion. Although the coexistence of TA and IBD is uncommon, both seem to be strongly associated through pathophysiological pathways. |
| format | Article |
| id | doaj-art-30a6a60d7249444ba88b2cedb32d5ed5 |
| institution | Kabale University |
| issn | 1687-6121 1687-630X |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Gastroenterology Research and Practice |
| spelling | doaj-art-30a6a60d7249444ba88b2cedb32d5ed52025-02-03T06:05:16ZengWileyGastroenterology Research and Practice1687-61211687-630X2021-01-01202110.1155/2021/88318678831867Coexistence of Takayasu’s Arteritis in Patients with Inflammatory Bowel DiseasesCamilla de Almeida Martins0Ana Elisa Rabe Caon1Carolina Bortolozzo Graciolli Facanali2Carlos Walter Sobrado3Sergio Carlos Nahas4Rosa Maria Rodrigues Pereira5Reuma Margalit-Yehuda6Uri Kopylov7Natalia Sousa Freitas Queiroz8Department of Gastroenterology and Division of Colorectal Surgery, University of Sao Paulo School of Medicine, São Paulo, BrazilDepartment of Gastroenterology and Division of Colorectal Surgery, University of Sao Paulo School of Medicine, São Paulo, BrazilDepartment of Gastroenterology and Division of Colorectal Surgery, University of Sao Paulo School of Medicine, São Paulo, BrazilDepartment of Gastroenterology and Division of Colorectal Surgery, University of Sao Paulo School of Medicine, São Paulo, BrazilDepartment of Gastroenterology and Division of Colorectal Surgery, University of Sao Paulo School of Medicine, São Paulo, BrazilDepartment of Rheumatology, University of Sao Paulo School of Medicine, São Paulo, BrazilGastroenterology Institute, Sheba Medical Center Tel Hashomer, Sackler School of Medicine, Tel-Aviv University, Tel Aviv, IsraelGastroenterology Institute, Sheba Medical Center Tel Hashomer, Sackler School of Medicine, Tel-Aviv University, Tel Aviv, IsraelDepartment of Gastroenterology and Division of Colorectal Surgery, University of Sao Paulo School of Medicine, São Paulo, BrazilBackground. Takayasu’s arteritis (TA) and inflammatory bowel disease (IBD) are chronic inflammatory granulomatous disorders that have rarely been concomitantly reported in case reports and small case series. Objective. We report a series of seven cases of TA and IBD association in two referral centers with a comprehensive review of literature. Methods. We analyzed retrospectively the electronic medical charts of TA-IBD patients at the University Hospital of São Paulo, Brazil, and at the Sheba Medical Center at Tel Aviv University, Israel. Results. Overall, five patients had Crohn’s disease (DC) and two had ulcerative colitis (UC), and they were mostly female and non-Asian. All patients developed IBD first and, subsequently, TA. Two underwent colectomy and one ileocecectomy due to IBD activity, while three required cardiovascular surgery due to TA activity. Most patients are currently in clinical remission of both diseases with conventional drug treatment. Conclusion. Although the coexistence of TA and IBD is uncommon, both seem to be strongly associated through pathophysiological pathways.http://dx.doi.org/10.1155/2021/8831867 |
| spellingShingle | Camilla de Almeida Martins Ana Elisa Rabe Caon Carolina Bortolozzo Graciolli Facanali Carlos Walter Sobrado Sergio Carlos Nahas Rosa Maria Rodrigues Pereira Reuma Margalit-Yehuda Uri Kopylov Natalia Sousa Freitas Queiroz Coexistence of Takayasu’s Arteritis in Patients with Inflammatory Bowel Diseases Gastroenterology Research and Practice |
| title | Coexistence of Takayasu’s Arteritis in Patients with Inflammatory Bowel Diseases |
| title_full | Coexistence of Takayasu’s Arteritis in Patients with Inflammatory Bowel Diseases |
| title_fullStr | Coexistence of Takayasu’s Arteritis in Patients with Inflammatory Bowel Diseases |
| title_full_unstemmed | Coexistence of Takayasu’s Arteritis in Patients with Inflammatory Bowel Diseases |
| title_short | Coexistence of Takayasu’s Arteritis in Patients with Inflammatory Bowel Diseases |
| title_sort | coexistence of takayasu s arteritis in patients with inflammatory bowel diseases |
| url | http://dx.doi.org/10.1155/2021/8831867 |
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