Combination therapy of GnRHa, RhGH and anastrozole to improve final adult height deficit in CAH children with CPP

Combination therapy of GnRHa, RhGH and anastrozole to improve final adult height deficit in CAH children with CPP

Abstract Background To investigate the clinical and genetic characteristics of classic congenital adrenal hyperplasia (CAH) patients. To determine whether gonadotropin-releasing hormone analogs (GnRHa) + recombinant human growth hormone (rhGH) + Anastrozole combined therapy improves the final adult...

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Bibliographic Details
Main Authors: Xiaoxiao Liu, Fei Liu, Yingyi Qi, Xinyi Han, Shifeng Ma, Rongxiu Zheng
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Pediatrics
Subjects:
21 Hydroxylase deficiency
CYP21A2 gene
Central precocious puberty
GnRHa
RhGH
Anastrozole
Online Access:https://doi.org/10.1186/s12887-025-05703-8
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