HisCoM-PAGE: software for hierarchical structural component models for pathway analysis of gene expression data
To identify pathways associated with survival phenotypes using gene expression data, we recently proposed the hierarchical structural component model for pathway analysis of gene expression data (HisCoM-PAGE) method. The HisCoM-PAGE software can consider hierarchical structural relationships between...
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| Format: | Article |
| Language: | English |
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BioMed Central
2019-12-01
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| Series: | Genomics & Informatics |
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| Online Access: | http://genominfo.org/upload/pdf/gi-2019-17-4-e45.pdf |
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| _version_ | 1832570551555588096 |
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| author | Lydia Mok Taesung Park |
| author_facet | Lydia Mok Taesung Park |
| author_sort | Lydia Mok |
| collection | DOAJ |
| description | To identify pathways associated with survival phenotypes using gene expression data, we recently proposed the hierarchical structural component model for pathway analysis of gene expression data (HisCoM-PAGE) method. The HisCoM-PAGE software can consider hierarchical structural relationships between genes and pathways and analyze multiple pathways simultaneously. It can be applied to various types of gene expression data, such as microarray data or RNA sequencing data. We expect that the HisCoM-PAGE software will make our method more easily accessible to researchers who want to perform pathway analysis for survival times. |
| format | Article |
| id | doaj-art-309d4c06b1f6408aa064abca4986700f |
| institution | Kabale University |
| issn | 2234-0742 |
| language | English |
| publishDate | 2019-12-01 |
| publisher | BioMed Central |
| record_format | Article |
| series | Genomics & Informatics |
| spelling | doaj-art-309d4c06b1f6408aa064abca4986700f2025-02-02T15:00:50ZengBioMed CentralGenomics & Informatics2234-07422019-12-0117410.5808/GI.2019.17.4.e45589HisCoM-PAGE: software for hierarchical structural component models for pathway analysis of gene expression dataLydia Mok0Taesung Park1 Interdisciplinary Program in Bioinformatics, Seoul National University, Seoul 08826, Korea Interdisciplinary Program in Bioinformatics, Seoul National University, Seoul 08826, KoreaTo identify pathways associated with survival phenotypes using gene expression data, we recently proposed the hierarchical structural component model for pathway analysis of gene expression data (HisCoM-PAGE) method. The HisCoM-PAGE software can consider hierarchical structural relationships between genes and pathways and analyze multiple pathways simultaneously. It can be applied to various types of gene expression data, such as microarray data or RNA sequencing data. We expect that the HisCoM-PAGE software will make our method more easily accessible to researchers who want to perform pathway analysis for survival times.http://genominfo.org/upload/pdf/gi-2019-17-4-e45.pdfgene expressionhierarchical component modelpathway analysissurvival phenotype |
| spellingShingle | Lydia Mok Taesung Park HisCoM-PAGE: software for hierarchical structural component models for pathway analysis of gene expression data Genomics & Informatics gene expression hierarchical component model pathway analysis survival phenotype |
| title | HisCoM-PAGE: software for hierarchical structural component models for pathway analysis of gene expression data |
| title_full | HisCoM-PAGE: software for hierarchical structural component models for pathway analysis of gene expression data |
| title_fullStr | HisCoM-PAGE: software for hierarchical structural component models for pathway analysis of gene expression data |
| title_full_unstemmed | HisCoM-PAGE: software for hierarchical structural component models for pathway analysis of gene expression data |
| title_short | HisCoM-PAGE: software for hierarchical structural component models for pathway analysis of gene expression data |
| title_sort | hiscom page software for hierarchical structural component models for pathway analysis of gene expression data |
| topic | gene expression hierarchical component model pathway analysis survival phenotype |
| url | http://genominfo.org/upload/pdf/gi-2019-17-4-e45.pdf |
| work_keys_str_mv | AT lydiamok hiscompagesoftwareforhierarchicalstructuralcomponentmodelsforpathwayanalysisofgeneexpressiondata AT taesungpark hiscompagesoftwareforhierarchicalstructuralcomponentmodelsforpathwayanalysisofgeneexpressiondata |