Investigation or the effects of prostaglandin f<sub>2α</sub>, furosemid and indomethacin on sperm characteristics in rams

This investigation was made to establish the effects of PGF<sub>2&#945;</sub>, furosemid, indomethacin and the combinations of these drugs on the sperm volume, viscosity, mass activity, motility, density and abnormal spermatozoa rate in rams. In the study, 70 Akkaraman rams, approxim...

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Main Authors: İbrahim Pirinçci, İzzet Karahan, Tanzer Bozkurt, Osman Güler
Format: Article
Language:English
Published: Selcuk University Press
Series:Eurasian Journal of Veterinary Sciences
Subjects:
Online Access:http://eurasianjvetsci.org/pdf.php3?id=350
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author İbrahim Pirinçci
İzzet Karahan
Tanzer Bozkurt
Osman Güler
author_facet İbrahim Pirinçci
İzzet Karahan
Tanzer Bozkurt
Osman Güler
author_sort İbrahim Pirinçci
collection DOAJ
description This investigation was made to establish the effects of PGF<sub>2&#945;</sub>, furosemid, indomethacin and the combinations of these drugs on the sperm volume, viscosity, mass activity, motility, density and abnormal spermatozoa rate in rams. In the study, 70 Akkaraman rams, approximately 2 years old were used. PGF<sub>2&#945;</sub> (0.1, 0.2 and 0.3 mg/ kg), furosemid (2.0, 4.0 and 6.0 mg/kg). indomethacin (3.0, 6.0 and 9,0 mg/kg) and the combinations of these drugs were intramuscularly given the animals In one dose and in doses following on each other's four days. The sperm samples were collected after administrations. Sperm characteristics were determined in the samples. The sperm volume. motility and density were established to decrease but the increase in abnormal sperm rate in the sperm samples in the rams given in one dose and in doses following on each other's four days PGF<sub>2&#945;</sub> and furosemid. However, sperm characteristics weren't altered in the rams given indomethacin. In conclusion, it was decided that prostaglandins and drugs effecting prostaglandin synthesis could alter sperm production and sperm characteristics.
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institution Kabale University
issn 1309-6958
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language English
publisher Selcuk University Press
record_format Article
series Eurasian Journal of Veterinary Sciences
spelling doaj-art-309292e1b0124e01b96eddecbf15e0b92025-02-03T11:25:45ZengSelcuk University PressEurasian Journal of Veterinary Sciences1309-69582146-19531718388350Investigation or the effects of prostaglandin f&lt;sub&gt;2&#945;&lt;/sub&gt;, furosemid and indomethacin on sperm characteristics in ramsİbrahim Pirinçci0İzzet Karahan1Tanzer Bozkurt2Osman Güler3F.Ü. Veteriner Fakültesi, Farmakoloji ve Toksikoloji Ab. Dalı, ELAZIĞF.Ü. Veteriner Fakültesi, Farmakoloji ve Toksikoloji Ab. Dalı, ELAZIĞF.Ü. Veteriner Fakültesi, Dölerme ve Suni Tohumlama Ab. Dalı, ELAZIĞT.K.B.'lığı Veteriner Kontrol ve Araştırma Enstitüsü, ELAZIĞThis investigation was made to establish the effects of PGF<sub>2&#945;</sub>, furosemid, indomethacin and the combinations of these drugs on the sperm volume, viscosity, mass activity, motility, density and abnormal spermatozoa rate in rams. In the study, 70 Akkaraman rams, approximately 2 years old were used. PGF<sub>2&#945;</sub> (0.1, 0.2 and 0.3 mg/ kg), furosemid (2.0, 4.0 and 6.0 mg/kg). indomethacin (3.0, 6.0 and 9,0 mg/kg) and the combinations of these drugs were intramuscularly given the animals In one dose and in doses following on each other's four days. The sperm samples were collected after administrations. Sperm characteristics were determined in the samples. The sperm volume. motility and density were established to decrease but the increase in abnormal sperm rate in the sperm samples in the rams given in one dose and in doses following on each other's four days PGF<sub>2&#945;</sub> and furosemid. However, sperm characteristics weren't altered in the rams given indomethacin. In conclusion, it was decided that prostaglandins and drugs effecting prostaglandin synthesis could alter sperm production and sperm characteristics.http://eurasianjvetsci.org/pdf.php3?id=350prostaglandin f2 alphafurosemidindomethacinsperm characteristicsram
spellingShingle İbrahim Pirinçci
İzzet Karahan
Tanzer Bozkurt
Osman Güler
Investigation or the effects of prostaglandin f&lt;sub&gt;2&#945;&lt;/sub&gt;, furosemid and indomethacin on sperm characteristics in rams
Eurasian Journal of Veterinary Sciences
prostaglandin f2 alpha
furosemid
indomethacin
sperm characteristics
ram
title Investigation or the effects of prostaglandin f&lt;sub&gt;2&#945;&lt;/sub&gt;, furosemid and indomethacin on sperm characteristics in rams
title_full Investigation or the effects of prostaglandin f&lt;sub&gt;2&#945;&lt;/sub&gt;, furosemid and indomethacin on sperm characteristics in rams
title_fullStr Investigation or the effects of prostaglandin f&lt;sub&gt;2&#945;&lt;/sub&gt;, furosemid and indomethacin on sperm characteristics in rams
title_full_unstemmed Investigation or the effects of prostaglandin f&lt;sub&gt;2&#945;&lt;/sub&gt;, furosemid and indomethacin on sperm characteristics in rams
title_short Investigation or the effects of prostaglandin f&lt;sub&gt;2&#945;&lt;/sub&gt;, furosemid and indomethacin on sperm characteristics in rams
title_sort investigation or the effects of prostaglandin f lt sub gt 2 945 lt sub gt furosemid and indomethacin on sperm characteristics in rams
topic prostaglandin f2 alpha
furosemid
indomethacin
sperm characteristics
ram
url http://eurasianjvetsci.org/pdf.php3?id=350
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AT tanzerbozkurt investigationortheeffectsofprostaglandinfltsubgt2945ltsubgtfurosemidandindomethacinonspermcharacteristicsinrams
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