Investigation or the effects of prostaglandin f<sub>2α</sub>, furosemid and indomethacin on sperm characteristics in rams
This investigation was made to establish the effects of PGF<sub>2α</sub>, furosemid, indomethacin and the combinations of these drugs on the sperm volume, viscosity, mass activity, motility, density and abnormal spermatozoa rate in rams. In the study, 70 Akkaraman rams, approxim...
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Selcuk University Press
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Series: | Eurasian Journal of Veterinary Sciences |
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author | İbrahim Pirinçci İzzet Karahan Tanzer Bozkurt Osman Güler |
author_facet | İbrahim Pirinçci İzzet Karahan Tanzer Bozkurt Osman Güler |
author_sort | İbrahim Pirinçci |
collection | DOAJ |
description | This investigation was made to establish the effects of PGF<sub>2α</sub>, furosemid, indomethacin and the combinations of these drugs on the sperm volume, viscosity, mass activity, motility, density and abnormal spermatozoa rate in rams. In the study, 70 Akkaraman rams, approximately 2 years old were used. PGF<sub>2α</sub> (0.1, 0.2 and 0.3 mg/ kg), furosemid (2.0, 4.0 and 6.0 mg/kg). indomethacin (3.0, 6.0 and 9,0 mg/kg) and the combinations of these drugs were intramuscularly given the animals In one dose and in doses following on each other's four days. The sperm samples were collected after administrations. Sperm characteristics were determined in the samples. The sperm volume. motility and density were established to decrease but the increase in abnormal sperm rate in the sperm samples in the rams given in one dose and in doses following on each other's four days PGF<sub>2α</sub> and furosemid. However, sperm characteristics weren't altered in the rams given indomethacin. In conclusion, it was decided that prostaglandins and drugs effecting prostaglandin synthesis could alter sperm production and sperm characteristics. |
format | Article |
id | doaj-art-309292e1b0124e01b96eddecbf15e0b9 |
institution | Kabale University |
issn | 1309-6958 2146-1953 |
language | English |
publisher | Selcuk University Press |
record_format | Article |
series | Eurasian Journal of Veterinary Sciences |
spelling | doaj-art-309292e1b0124e01b96eddecbf15e0b92025-02-03T11:25:45ZengSelcuk University PressEurasian Journal of Veterinary Sciences1309-69582146-19531718388350Investigation or the effects of prostaglandin f<sub>2α</sub>, furosemid and indomethacin on sperm characteristics in ramsİbrahim Pirinçci0İzzet Karahan1Tanzer Bozkurt2Osman Güler3F.Ü. Veteriner Fakültesi, Farmakoloji ve Toksikoloji Ab. Dalı, ELAZIĞF.Ü. Veteriner Fakültesi, Farmakoloji ve Toksikoloji Ab. Dalı, ELAZIĞF.Ü. Veteriner Fakültesi, Dölerme ve Suni Tohumlama Ab. Dalı, ELAZIĞT.K.B.'lığı Veteriner Kontrol ve Araştırma Enstitüsü, ELAZIĞThis investigation was made to establish the effects of PGF<sub>2α</sub>, furosemid, indomethacin and the combinations of these drugs on the sperm volume, viscosity, mass activity, motility, density and abnormal spermatozoa rate in rams. In the study, 70 Akkaraman rams, approximately 2 years old were used. PGF<sub>2α</sub> (0.1, 0.2 and 0.3 mg/ kg), furosemid (2.0, 4.0 and 6.0 mg/kg). indomethacin (3.0, 6.0 and 9,0 mg/kg) and the combinations of these drugs were intramuscularly given the animals In one dose and in doses following on each other's four days. The sperm samples were collected after administrations. Sperm characteristics were determined in the samples. The sperm volume. motility and density were established to decrease but the increase in abnormal sperm rate in the sperm samples in the rams given in one dose and in doses following on each other's four days PGF<sub>2α</sub> and furosemid. However, sperm characteristics weren't altered in the rams given indomethacin. In conclusion, it was decided that prostaglandins and drugs effecting prostaglandin synthesis could alter sperm production and sperm characteristics.http://eurasianjvetsci.org/pdf.php3?id=350prostaglandin f2 alphafurosemidindomethacinsperm characteristicsram |
spellingShingle | İbrahim Pirinçci İzzet Karahan Tanzer Bozkurt Osman Güler Investigation or the effects of prostaglandin f<sub>2α</sub>, furosemid and indomethacin on sperm characteristics in rams Eurasian Journal of Veterinary Sciences prostaglandin f2 alpha furosemid indomethacin sperm characteristics ram |
title | Investigation or the effects of prostaglandin f<sub>2α</sub>, furosemid and indomethacin on sperm characteristics in rams |
title_full | Investigation or the effects of prostaglandin f<sub>2α</sub>, furosemid and indomethacin on sperm characteristics in rams |
title_fullStr | Investigation or the effects of prostaglandin f<sub>2α</sub>, furosemid and indomethacin on sperm characteristics in rams |
title_full_unstemmed | Investigation or the effects of prostaglandin f<sub>2α</sub>, furosemid and indomethacin on sperm characteristics in rams |
title_short | Investigation or the effects of prostaglandin f<sub>2α</sub>, furosemid and indomethacin on sperm characteristics in rams |
title_sort | investigation or the effects of prostaglandin f lt sub gt 2 945 lt sub gt furosemid and indomethacin on sperm characteristics in rams |
topic | prostaglandin f2 alpha furosemid indomethacin sperm characteristics ram |
url | http://eurasianjvetsci.org/pdf.php3?id=350 |
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