Milk-derived extracellular vesicles and gut health
Abstract Milk is a nutrient-rich liquid produced by mammals, offering various health benefits due to its composition of proteins, fats, carbohydrates, vitamins, and minerals. Beyond traditional nutritional aspects, recent research has focused on extracellular vesicles (EVs) found in milk and their p...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2025-01-01
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| Series: | npj Science of Food |
| Online Access: | https://doi.org/10.1038/s41538-025-00375-1 |
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| _version_ | 1832571223657152512 |
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| author | Barathan Muttiah Jia Xian Law |
| author_facet | Barathan Muttiah Jia Xian Law |
| author_sort | Barathan Muttiah |
| collection | DOAJ |
| description | Abstract Milk is a nutrient-rich liquid produced by mammals, offering various health benefits due to its composition of proteins, fats, carbohydrates, vitamins, and minerals. Beyond traditional nutritional aspects, recent research has focused on extracellular vesicles (EVs) found in milk and their potential health benefits, especially for gastrointestinal (GI) health. Milk-derived EVs have been shown to influence gut microbiota, promote gut barrier integrity, support tissue repair and regeneration, modulate immune responses, and potentially aid in managing conditions like inflammatory bowel disease (IBD) and colorectal cancer. This review discusses the current understanding of milk-EVs’ effects on gut health, highlighting their potential therapeutic applications and future research directions. These findings underscore the promising role of milk-derived EVs in advancing GI health and therapeutics, paving the way for innovative approaches in oral drug delivery and targeted treatments for GI disorders. |
| format | Article |
| id | doaj-art-308b1334576e4e679e6940e2ce4fcaf1 |
| institution | Kabale University |
| issn | 2396-8370 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | npj Science of Food |
| spelling | doaj-art-308b1334576e4e679e6940e2ce4fcaf12025-02-02T12:44:16ZengNature Portfolionpj Science of Food2396-83702025-01-019111210.1038/s41538-025-00375-1Milk-derived extracellular vesicles and gut healthBarathan Muttiah0Jia Xian Law1Department of Tissue Engineering and Regenerative Medicine, Faculty of Medicine, Universiti Kebangsaan MalaysiaDepartment of Tissue Engineering and Regenerative Medicine, Faculty of Medicine, Universiti Kebangsaan MalaysiaAbstract Milk is a nutrient-rich liquid produced by mammals, offering various health benefits due to its composition of proteins, fats, carbohydrates, vitamins, and minerals. Beyond traditional nutritional aspects, recent research has focused on extracellular vesicles (EVs) found in milk and their potential health benefits, especially for gastrointestinal (GI) health. Milk-derived EVs have been shown to influence gut microbiota, promote gut barrier integrity, support tissue repair and regeneration, modulate immune responses, and potentially aid in managing conditions like inflammatory bowel disease (IBD) and colorectal cancer. This review discusses the current understanding of milk-EVs’ effects on gut health, highlighting their potential therapeutic applications and future research directions. These findings underscore the promising role of milk-derived EVs in advancing GI health and therapeutics, paving the way for innovative approaches in oral drug delivery and targeted treatments for GI disorders.https://doi.org/10.1038/s41538-025-00375-1 |
| spellingShingle | Barathan Muttiah Jia Xian Law Milk-derived extracellular vesicles and gut health npj Science of Food |
| title | Milk-derived extracellular vesicles and gut health |
| title_full | Milk-derived extracellular vesicles and gut health |
| title_fullStr | Milk-derived extracellular vesicles and gut health |
| title_full_unstemmed | Milk-derived extracellular vesicles and gut health |
| title_short | Milk-derived extracellular vesicles and gut health |
| title_sort | milk derived extracellular vesicles and gut health |
| url | https://doi.org/10.1038/s41538-025-00375-1 |
| work_keys_str_mv | AT barathanmuttiah milkderivedextracellularvesiclesandguthealth AT jiaxianlaw milkderivedextracellularvesiclesandguthealth |