Choroidal Detachment after XEN Gel Stent Implantation

Background. The purpose of this study is to estimate the incidence of choroidal detachment (CD) after XEN gel stent implant surgery and to evaluate the associated factors. Methods. We reviewed the clinical charts of 126 patients who underwent XEN implantation between March 1, 2016, and December 31,...

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Main Authors: Carlo Alberto Cutolo, Letizia Negri, Sara Olivari, Francesca Cappelli, Carlo Enrico Traverso, Michele Iester
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Journal of Ophthalmology
Online Access:http://dx.doi.org/10.1155/2021/6674505
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author Carlo Alberto Cutolo
Letizia Negri
Sara Olivari
Francesca Cappelli
Carlo Enrico Traverso
Michele Iester
author_facet Carlo Alberto Cutolo
Letizia Negri
Sara Olivari
Francesca Cappelli
Carlo Enrico Traverso
Michele Iester
author_sort Carlo Alberto Cutolo
collection DOAJ
description Background. The purpose of this study is to estimate the incidence of choroidal detachment (CD) after XEN gel stent implant surgery and to evaluate the associated factors. Methods. We reviewed the clinical charts of 126 patients who underwent XEN implantation between March 1, 2016, and December 31, 2018 at the University Eye Clinic of Genoa. Ocular, demographics, and perioperative factor were registered and analysed. Univariate and multivariate logistic analysis were performed to investigate factors associated with CD occurrence. Results. Of the 126 patients, 25 (19.8%) developed a choroidal detachment after XEN gel stent implant surgery. The mean period between surgery and CD detection was 5.84 ± 1.77 days. The mean intraocular pressure (IOP) at the time of CD diagnosis was 6.4 ± 3.1 mmHg. Age (OR = 1.10, p<0.019), early postoperative IOP (OR = 0.70, p<0.001), and number of preoperative IOP-lowering drugs (OR = 5.70, p<0.001) were significantly associated with CD presence. Complete resolution was observed in all the cases. Wide-field imaging and ultrasonography were useful tools to diagnose and follow up CD until resolution. Conclusions. When carefully investigated, CD is a relatively common complication after XEN gel stent implant procedure. Older age, lower postoperative IOP, and higher number of preoperative IOP-lowering drugs were significantly associated with the development of CD.
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spelling doaj-art-306b0af3dad14f21847c8fa50708c2b22025-02-03T01:04:26ZengWileyJournal of Ophthalmology2090-004X2090-00582021-01-01202110.1155/2021/66745056674505Choroidal Detachment after XEN Gel Stent ImplantationCarlo Alberto Cutolo0Letizia Negri1Sara Olivari2Francesca Cappelli3Carlo Enrico Traverso4Michele Iester5Clinica Oculistica, Department of Neuroscience Rehabilitation Ophthalmology Genetics Maternal and Child Health (DiNOGMI), University of Genoa, Genoa, ItalyClinica Oculistica, Department of Neuroscience Rehabilitation Ophthalmology Genetics Maternal and Child Health (DiNOGMI), University of Genoa, Genoa, ItalyClinica Oculistica, Department of Neuroscience Rehabilitation Ophthalmology Genetics Maternal and Child Health (DiNOGMI), University of Genoa, Genoa, ItalyClinica Oculistica, Department of Neuroscience Rehabilitation Ophthalmology Genetics Maternal and Child Health (DiNOGMI), University of Genoa, Genoa, ItalyClinica Oculistica, Department of Neuroscience Rehabilitation Ophthalmology Genetics Maternal and Child Health (DiNOGMI), University of Genoa, Genoa, ItalyClinica Oculistica, Department of Neuroscience Rehabilitation Ophthalmology Genetics Maternal and Child Health (DiNOGMI), University of Genoa, Genoa, ItalyBackground. The purpose of this study is to estimate the incidence of choroidal detachment (CD) after XEN gel stent implant surgery and to evaluate the associated factors. Methods. We reviewed the clinical charts of 126 patients who underwent XEN implantation between March 1, 2016, and December 31, 2018 at the University Eye Clinic of Genoa. Ocular, demographics, and perioperative factor were registered and analysed. Univariate and multivariate logistic analysis were performed to investigate factors associated with CD occurrence. Results. Of the 126 patients, 25 (19.8%) developed a choroidal detachment after XEN gel stent implant surgery. The mean period between surgery and CD detection was 5.84 ± 1.77 days. The mean intraocular pressure (IOP) at the time of CD diagnosis was 6.4 ± 3.1 mmHg. Age (OR = 1.10, p<0.019), early postoperative IOP (OR = 0.70, p<0.001), and number of preoperative IOP-lowering drugs (OR = 5.70, p<0.001) were significantly associated with CD presence. Complete resolution was observed in all the cases. Wide-field imaging and ultrasonography were useful tools to diagnose and follow up CD until resolution. Conclusions. When carefully investigated, CD is a relatively common complication after XEN gel stent implant procedure. Older age, lower postoperative IOP, and higher number of preoperative IOP-lowering drugs were significantly associated with the development of CD.http://dx.doi.org/10.1155/2021/6674505
spellingShingle Carlo Alberto Cutolo
Letizia Negri
Sara Olivari
Francesca Cappelli
Carlo Enrico Traverso
Michele Iester
Choroidal Detachment after XEN Gel Stent Implantation
Journal of Ophthalmology
title Choroidal Detachment after XEN Gel Stent Implantation
title_full Choroidal Detachment after XEN Gel Stent Implantation
title_fullStr Choroidal Detachment after XEN Gel Stent Implantation
title_full_unstemmed Choroidal Detachment after XEN Gel Stent Implantation
title_short Choroidal Detachment after XEN Gel Stent Implantation
title_sort choroidal detachment after xen gel stent implantation
url http://dx.doi.org/10.1155/2021/6674505
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