Association of daily step counts and step intensity with mortality among US adults: a cross–sectional study of NHANES 2005–2006
Abstract Background & aims We aimed to describe the dose–response relationship between daily step counts and intensity with respect to all–cause mortality among US adults diagnosed with metabolic dysfunction–associated steatotic liver disease (MASLD). Methods Using data from the National Health...
Saved in:
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-01-01
|
| Series: | BMC Gastroenterology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12876-025-03606-7 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832585623971561472 |
|---|---|
| author | Tianzhou Peng Changhao Liu Ti Yang Leyi Liao Qingping Li Hanbiao Liang Jiapeng Zhang Chen Xie Kai Wang Chuanjiang Li |
| author_facet | Tianzhou Peng Changhao Liu Ti Yang Leyi Liao Qingping Li Hanbiao Liang Jiapeng Zhang Chen Xie Kai Wang Chuanjiang Li |
| author_sort | Tianzhou Peng |
| collection | DOAJ |
| description | Abstract Background & aims We aimed to describe the dose–response relationship between daily step counts and intensity with respect to all–cause mortality among US adults diagnosed with metabolic dysfunction–associated steatotic liver disease (MASLD). Methods Using data from the National Health and Nutrition Examination Survey (NHANES) database spanning from 2005 to 2006, a cross–sectional study included 1,108 participants was performed to assess the relationship between daily step counts and step intensity with mortality. Results A total of 1,108 participants from the NHANES study were included, with a mean age of 49.5 ± 0.9 years. The sample consisted of 533 (48.1%) women, 809(73%) non–Hispanic whites, 122 (10.8%) non–Hispanic blacks, 133 (12.0%) Hispanic, and 44 (4.2%) individuals of other racial backgrounds. Using multivariable–adjusted Cox proportional hazards models, we found that compared to participants in the light–step group, there was significantly lower risk of mortality in the moderate (hazard ratio [HR], 0.47 [95% CI, 0.32–0.69]), high (HR, 0.35 [95% CI, 0.21–0.61]) and vigorous (HR,0.45 [95% CI, 0.22–0.93]) step groups. Sensitivity and subgroup analyses confirmed that the association between step count and mortality remained robust. However, after adjusting for all covariates, greater step intensity was not significantly associated with lower mortality. Further analysis revealed that age, BMI, and self–rated health could have confounded the relationship between step intensity and survival, potentially obscuring any direct effect of step intensity on mortality. Conclusions Accumulating a higher number of daily steps, rather than focusing on step intensity, was associated with a lower risk of all–cause mortality in individuals with MASLD. Our findings suggest that achieving 10,000 steps per day may be optimal for reducing the risk of all–cause mortality risk in this population. |
| format | Article |
| id | doaj-art-305b7d05a77e4d14ba45451a90a1aa2f |
| institution | Kabale University |
| issn | 1471-230X |
| language | English |
| publishDate | 2025-01-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Gastroenterology |
| spelling | doaj-art-305b7d05a77e4d14ba45451a90a1aa2f2025-01-26T12:36:25ZengBMCBMC Gastroenterology1471-230X2025-01-0125111410.1186/s12876-025-03606-7Association of daily step counts and step intensity with mortality among US adults: a cross–sectional study of NHANES 2005–2006Tianzhou Peng0Changhao Liu1Ti Yang2Leyi Liao3Qingping Li4Hanbiao Liang5Jiapeng Zhang6Chen Xie7Kai Wang8Chuanjiang Li9Division of Hepatobiliopancreatic Surgery, Department of General Surgery, Nanfang Hospital, Southern Medical UniversityDivision of Hepatobiliopancreatic Surgery, Department of General Surgery, Nanfang Hospital, Southern Medical UniversityDivision of Hepatobiliopancreatic Surgery, Department of General Surgery, Nanfang Hospital, Southern Medical UniversityDivision of Hepatobiliopancreatic Surgery, Department of General Surgery, Nanfang Hospital, Southern Medical UniversityDivision of Hepatobiliopancreatic Surgery, Department of General Surgery, Nanfang Hospital, Southern Medical UniversityDivision of Hepatobiliopancreatic Surgery, Department of General Surgery, Nanfang Hospital, Southern Medical UniversityDivision of Hepatobiliopancreatic Surgery, Department of General Surgery, Nanfang Hospital, Southern Medical UniversityDivision of Hepatobiliopancreatic Surgery, Department of General Surgery, Nanfang Hospital, Southern Medical UniversityDivision of Hepatobiliopancreatic Surgery, Department of General Surgery, Nanfang Hospital, Southern Medical UniversityDivision of Hepatobiliopancreatic Surgery, Department of General Surgery, Nanfang Hospital, Southern Medical UniversityAbstract Background & aims We aimed to describe the dose–response relationship between daily step counts and intensity with respect to all–cause mortality among US adults diagnosed with metabolic dysfunction–associated steatotic liver disease (MASLD). Methods Using data from the National Health and Nutrition Examination Survey (NHANES) database spanning from 2005 to 2006, a cross–sectional study included 1,108 participants was performed to assess the relationship between daily step counts and step intensity with mortality. Results A total of 1,108 participants from the NHANES study were included, with a mean age of 49.5 ± 0.9 years. The sample consisted of 533 (48.1%) women, 809(73%) non–Hispanic whites, 122 (10.8%) non–Hispanic blacks, 133 (12.0%) Hispanic, and 44 (4.2%) individuals of other racial backgrounds. Using multivariable–adjusted Cox proportional hazards models, we found that compared to participants in the light–step group, there was significantly lower risk of mortality in the moderate (hazard ratio [HR], 0.47 [95% CI, 0.32–0.69]), high (HR, 0.35 [95% CI, 0.21–0.61]) and vigorous (HR,0.45 [95% CI, 0.22–0.93]) step groups. Sensitivity and subgroup analyses confirmed that the association between step count and mortality remained robust. However, after adjusting for all covariates, greater step intensity was not significantly associated with lower mortality. Further analysis revealed that age, BMI, and self–rated health could have confounded the relationship between step intensity and survival, potentially obscuring any direct effect of step intensity on mortality. Conclusions Accumulating a higher number of daily steps, rather than focusing on step intensity, was associated with a lower risk of all–cause mortality in individuals with MASLD. Our findings suggest that achieving 10,000 steps per day may be optimal for reducing the risk of all–cause mortality risk in this population.https://doi.org/10.1186/s12876-025-03606-7Step countsStep intensityAll–cause mortalityMetabolic dysfunction–associated steatotic liver diseasePhysical activity |
| spellingShingle | Tianzhou Peng Changhao Liu Ti Yang Leyi Liao Qingping Li Hanbiao Liang Jiapeng Zhang Chen Xie Kai Wang Chuanjiang Li Association of daily step counts and step intensity with mortality among US adults: a cross–sectional study of NHANES 2005–2006 BMC Gastroenterology Step counts Step intensity All–cause mortality Metabolic dysfunction–associated steatotic liver disease Physical activity |
| title | Association of daily step counts and step intensity with mortality among US adults: a cross–sectional study of NHANES 2005–2006 |
| title_full | Association of daily step counts and step intensity with mortality among US adults: a cross–sectional study of NHANES 2005–2006 |
| title_fullStr | Association of daily step counts and step intensity with mortality among US adults: a cross–sectional study of NHANES 2005–2006 |
| title_full_unstemmed | Association of daily step counts and step intensity with mortality among US adults: a cross–sectional study of NHANES 2005–2006 |
| title_short | Association of daily step counts and step intensity with mortality among US adults: a cross–sectional study of NHANES 2005–2006 |
| title_sort | association of daily step counts and step intensity with mortality among us adults a cross sectional study of nhanes 2005 2006 |
| topic | Step counts Step intensity All–cause mortality Metabolic dysfunction–associated steatotic liver disease Physical activity |
| url | https://doi.org/10.1186/s12876-025-03606-7 |
| work_keys_str_mv | AT tianzhoupeng associationofdailystepcountsandstepintensitywithmortalityamongusadultsacrosssectionalstudyofnhanes20052006 AT changhaoliu associationofdailystepcountsandstepintensitywithmortalityamongusadultsacrosssectionalstudyofnhanes20052006 AT tiyang associationofdailystepcountsandstepintensitywithmortalityamongusadultsacrosssectionalstudyofnhanes20052006 AT leyiliao associationofdailystepcountsandstepintensitywithmortalityamongusadultsacrosssectionalstudyofnhanes20052006 AT qingpingli associationofdailystepcountsandstepintensitywithmortalityamongusadultsacrosssectionalstudyofnhanes20052006 AT hanbiaoliang associationofdailystepcountsandstepintensitywithmortalityamongusadultsacrosssectionalstudyofnhanes20052006 AT jiapengzhang associationofdailystepcountsandstepintensitywithmortalityamongusadultsacrosssectionalstudyofnhanes20052006 AT chenxie associationofdailystepcountsandstepintensitywithmortalityamongusadultsacrosssectionalstudyofnhanes20052006 AT kaiwang associationofdailystepcountsandstepintensitywithmortalityamongusadultsacrosssectionalstudyofnhanes20052006 AT chuanjiangli associationofdailystepcountsandstepintensitywithmortalityamongusadultsacrosssectionalstudyofnhanes20052006 |