Somatic LKB1 mutations promote cervical cancer progression.
Human Papilloma Virus (HPV) is the etiologic agent for cervical cancer. Yet, infection with HPV is not sufficient to cause cervical cancer, because most infected women develop transient epithelial dysplasias that spontaneously regress. Progression to invasive cancer has been attributed to diverse ho...
Saved in:
| Main Authors: | Shana N Wingo, Teresa D Gallardo, Esra A Akbay, Mei-Chi Liang, Cristina M Contreras, Todd Boren, Takeshi Shimamura, David S Miller, Norman E Sharpless, Nabeel Bardeesy, David J Kwiatkowski, John O Schorge, Kwok-Kin Wong, Diego H Castrillon |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2009-01-01
|
| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0005137&type=printable |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Novel and potent MICA/B antibody is therapeutically effective in KRAS LKB1 mutant lung cancer models
by: Shohei Koyama, et al.
Published: (2025-01-01) -
Insights into targeting LKB1 in tumorigenesis
by: Charles B. Trelford, et al.
Published: (2025-03-01) -
LKB1 is an essential regulator of spermatozoa release during spermiation in the mammalian testis.
by: Fiona C Denison, et al.
Published: (2011-01-01) -
Sensory neuron LKB1 mediates ovarian and reproductive function
by: Melissa E Lenert, et al.
Published: (2024-11-01) -
LKB1 destabilizes microtubules in myoblasts and contributes to myoblast differentiation.
by: Isma Mian, et al.
Published: (2012-01-01)