Decoding the transmission and subsequent disability risks of rabineurodeficiency syndrome without recuperation

Abstract This study presents a novel approach focused on extensively addressing the dynamics of Rabineurodeficiency Syndrome by developing a mathematical compartmental model without recuperation. The equilibria of the rabies-free and present states are analyzed locally and globally. Real-world data...

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Main Authors: Yasir Ramzan, Bandar M. Fadhl, Shafiullah Niazai, Aziz Ullah Awan, Kamel Guedri
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-01066-3
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author Yasir Ramzan
Bandar M. Fadhl
Shafiullah Niazai
Aziz Ullah Awan
Kamel Guedri
author_facet Yasir Ramzan
Bandar M. Fadhl
Shafiullah Niazai
Aziz Ullah Awan
Kamel Guedri
author_sort Yasir Ramzan
collection DOAJ
description Abstract This study presents a novel approach focused on extensively addressing the dynamics of Rabineurodeficiency Syndrome by developing a mathematical compartmental model without recuperation. The equilibria of the rabies-free and present states are analyzed locally and globally. Real-world data on annual rabies cases are integrated to confirm and enhance the model’s accuracy. Likewise, a parameter estimation technique is employed to optimize the model, aiding in calculating the basic reproduction number. Sensitivity analysis examines the impact of critical parameters on transmission dynamics, providing a deeper understanding of the determining factors influencing disease spread. Visual representations of the relationship between essential parameters and the reproduction number offer valuable insights into factors influencing disease control. Advancing the understanding of Rabineurodeficiency Syndrome dynamics, the inclusive control actions to mitigate infectious diseases are evaluated, emphasizing the importance of accounting for individuals with disabilities.
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institution Kabale University
issn 2045-2322
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publishDate 2025-05-01
publisher Nature Portfolio
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series Scientific Reports
spelling doaj-art-3038bbcf5aaf443791948ce543f34e7c2025-08-20T03:48:18ZengNature PortfolioScientific Reports2045-23222025-05-0115111710.1038/s41598-025-01066-3Decoding the transmission and subsequent disability risks of rabineurodeficiency syndrome without recuperationYasir Ramzan0Bandar M. Fadhl1Shafiullah Niazai2Aziz Ullah Awan3Kamel Guedri4Department of Mathematics, Shanghai UniversityMechanical Engineering Department, College of Engineering and Architecture, Umm Al-Qura UniversityDepartment of Mathematics, Education Faculty, Laghman UniversityInstitute of Mathematics, University of the PunjabMechanical Engineering Department, College of Engineering and Architecture, Umm Al-Qura UniversityAbstract This study presents a novel approach focused on extensively addressing the dynamics of Rabineurodeficiency Syndrome by developing a mathematical compartmental model without recuperation. The equilibria of the rabies-free and present states are analyzed locally and globally. Real-world data on annual rabies cases are integrated to confirm and enhance the model’s accuracy. Likewise, a parameter estimation technique is employed to optimize the model, aiding in calculating the basic reproduction number. Sensitivity analysis examines the impact of critical parameters on transmission dynamics, providing a deeper understanding of the determining factors influencing disease spread. Visual representations of the relationship between essential parameters and the reproduction number offer valuable insights into factors influencing disease control. Advancing the understanding of Rabineurodeficiency Syndrome dynamics, the inclusive control actions to mitigate infectious diseases are evaluated, emphasizing the importance of accounting for individuals with disabilities.https://doi.org/10.1038/s41598-025-01066-3Rabineurodeficiency SyndromeMathematical FormulationStability AnalysisParameter EstimationSensitivity AnalysisControl Strategies
spellingShingle Yasir Ramzan
Bandar M. Fadhl
Shafiullah Niazai
Aziz Ullah Awan
Kamel Guedri
Decoding the transmission and subsequent disability risks of rabineurodeficiency syndrome without recuperation
Scientific Reports
Rabineurodeficiency Syndrome
Mathematical Formulation
Stability Analysis
Parameter Estimation
Sensitivity Analysis
Control Strategies
title Decoding the transmission and subsequent disability risks of rabineurodeficiency syndrome without recuperation
title_full Decoding the transmission and subsequent disability risks of rabineurodeficiency syndrome without recuperation
title_fullStr Decoding the transmission and subsequent disability risks of rabineurodeficiency syndrome without recuperation
title_full_unstemmed Decoding the transmission and subsequent disability risks of rabineurodeficiency syndrome without recuperation
title_short Decoding the transmission and subsequent disability risks of rabineurodeficiency syndrome without recuperation
title_sort decoding the transmission and subsequent disability risks of rabineurodeficiency syndrome without recuperation
topic Rabineurodeficiency Syndrome
Mathematical Formulation
Stability Analysis
Parameter Estimation
Sensitivity Analysis
Control Strategies
url https://doi.org/10.1038/s41598-025-01066-3
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