Design of studies on neoadjuvant therapy for intrahepatic cholangiocarcinoma
The high recurrence rate and dismal prognosis of localized intrahepatic cholangiocarcinoma (ICC) indicate the unmet need for effective adjuvant and neoadjuvant therapy. In recent years, progress has been made in immunotherapy and targeted therapy for the treatment of advanced biliary tract cancer (B...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-01-01
|
| Series: | Heliyon |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844024173872 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832573133676085248 |
|---|---|
| author | Yuan Cheng Xiangcheng Li |
| author_facet | Yuan Cheng Xiangcheng Li |
| author_sort | Yuan Cheng |
| collection | DOAJ |
| description | The high recurrence rate and dismal prognosis of localized intrahepatic cholangiocarcinoma (ICC) indicate the unmet need for effective adjuvant and neoadjuvant therapy. In recent years, progress has been made in immunotherapy and targeted therapy for the treatment of advanced biliary tract cancer (BTC), leading to clinical exploration of the provision of these therapies in the perioperative period. Based on years of experience in clinical research on hepatobiliary cancers, the authors discuss the design of studies on neoadjuvant therapy for ICC, aiming to provide references for future neoadjuvant studies. |
| format | Article |
| id | doaj-art-3016f79617bb48cb80c993901b1365cb |
| institution | Kabale University |
| issn | 2405-8440 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj-art-3016f79617bb48cb80c993901b1365cb2025-02-02T05:27:47ZengElsevierHeliyon2405-84402025-01-01112e41356Design of studies on neoadjuvant therapy for intrahepatic cholangiocarcinomaYuan Cheng0Xiangcheng Li1Department of Medical Oncology, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210002, ChinaHepatobiliary Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China; Corresponding author.The high recurrence rate and dismal prognosis of localized intrahepatic cholangiocarcinoma (ICC) indicate the unmet need for effective adjuvant and neoadjuvant therapy. In recent years, progress has been made in immunotherapy and targeted therapy for the treatment of advanced biliary tract cancer (BTC), leading to clinical exploration of the provision of these therapies in the perioperative period. Based on years of experience in clinical research on hepatobiliary cancers, the authors discuss the design of studies on neoadjuvant therapy for ICC, aiming to provide references for future neoadjuvant studies.http://www.sciencedirect.com/science/article/pii/S2405844024173872CholangiocarcinomaNeoadjuvantImmunotherapyTargeted therapyDesigns |
| spellingShingle | Yuan Cheng Xiangcheng Li Design of studies on neoadjuvant therapy for intrahepatic cholangiocarcinoma Heliyon Cholangiocarcinoma Neoadjuvant Immunotherapy Targeted therapy Designs |
| title | Design of studies on neoadjuvant therapy for intrahepatic cholangiocarcinoma |
| title_full | Design of studies on neoadjuvant therapy for intrahepatic cholangiocarcinoma |
| title_fullStr | Design of studies on neoadjuvant therapy for intrahepatic cholangiocarcinoma |
| title_full_unstemmed | Design of studies on neoadjuvant therapy for intrahepatic cholangiocarcinoma |
| title_short | Design of studies on neoadjuvant therapy for intrahepatic cholangiocarcinoma |
| title_sort | design of studies on neoadjuvant therapy for intrahepatic cholangiocarcinoma |
| topic | Cholangiocarcinoma Neoadjuvant Immunotherapy Targeted therapy Designs |
| url | http://www.sciencedirect.com/science/article/pii/S2405844024173872 |
| work_keys_str_mv | AT yuancheng designofstudiesonneoadjuvanttherapyforintrahepaticcholangiocarcinoma AT xiangchengli designofstudiesonneoadjuvanttherapyforintrahepaticcholangiocarcinoma |