Knockout of <i>dhx38</i> Causes Inner Ear Developmental Defects in Zebrafish

Knockout of <i>dhx38</i> Causes Inner Ear Developmental Defects in Zebrafish

<b>Background</b>: Alternative splicing is essential for the physiological and pathological development of the inner ear. Disruptions in this process can result in both syndromic and non-syndromic forms of hearing loss. DHX38, a DEAH box RNA helicase, is integral to pre-mRNA splicing reg...

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Bibliographic Details
Main Authors: Mengmeng Ren, Xiang Chen, Liyan Dai, Jiayi Tu, Hualei Hu, Xiaohan Sun, Jiong Luo, Pei Li, Yiyang Fu, Yuejie Zhu, Weiqiang Sun, Zhaohui Tang, Mugen Liu, Xiang Ren, Qunwei Lu
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Biomedicines
Subjects:
inner ear development
<i>dhx38</i>
zebrafish
cell apoptosis
DNA damage
Online Access:https://www.mdpi.com/2227-9059/13/1/20
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