Experimental and clinical ground of using of diquertin and ascorbic acid complex at monopolar ovary coagulation

There has been conducted a study of morphofunctional ovary changes at monopolar coagulation using histological, histochemical and ultra-microscopic techniques, and there have been evaluated hemorheologic factors and state of lipid peroxidation system (LPS) in postsurgical period. It has been proved...

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Main Authors: I. Yu. Bukharina, O. A. Tikhonovskaya, M. B. Plotnikov, M. S. Petrova, M. Yu. Maslov, Ye. S. Koschevets, S. V. Logvinov
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2003-06-01
Series:Бюллетень сибирской медицины
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Online Access:https://bulletin.ssmu.ru/jour/article/view/3747
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author I. Yu. Bukharina
O. A. Tikhonovskaya
M. B. Plotnikov
M. S. Petrova
M. Yu. Maslov
Ye. S. Koschevets
S. V. Logvinov
author_facet I. Yu. Bukharina
O. A. Tikhonovskaya
M. B. Plotnikov
M. S. Petrova
M. Yu. Maslov
Ye. S. Koschevets
S. V. Logvinov
author_sort I. Yu. Bukharina
collection DOAJ
description There has been conducted a study of morphofunctional ovary changes at monopolar coagulation using histological, histochemical and ultra-microscopic techniques, and there have been evaluated hemorheologic factors and state of lipid peroxidation system (LPS) in postsurgical period. It has been proved that electrocoagulation stimulates the follicle growth for a short time but damages the generative and endocrine ovary apparatus and causes evident hemodynamic changes in perifocal zone. At the same time the raise of blood viscosity and erythrocyte aggregation and LPS activation are occurring. Possessing hemorheologic and antioxidant properties ascovertin produces a protective effect on generative ovary apparatus and microcirculation in it. 48 women after laparoscopic operations on ovaries with the use of electrocoagulation have been examined prospectively. The women of the basic group took the diquertin and ascorbic acid complex prior to and after the surgery in addition to the basic therapy. There has been made an evaluation of LPS factors prior to and after the surgery, computed kymopertubation results and hormonic state in a 1 month after the surgery, frequency of pregnancy beginning. Prescription of diquertin and ascorbic acid complex under the developed procedure is pathogenetically reasonable, it allows to increase the quality of treatment after laparoscopic operations on ovaries and encourages the preservation of reproductive function of a female organism.
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record_format Article
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spelling doaj-art-2ff50ebbf7304dc1aa111d7fb87009b82025-08-20T03:37:19ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842003-06-0122263610.20538/1682-0363-2003-2-26-362370Experimental and clinical ground of using of diquertin and ascorbic acid complex at monopolar ovary coagulationI. Yu. Bukharina0O. A. Tikhonovskaya1M. B. Plotnikov2M. S. Petrova3M. Yu. Maslov4Ye. S. Koschevets5S. V. Logvinov6Сибирский государственный медицинский университет МЗ РФСибирский государственный медицинский университет МЗ РФНИИ фармакологии ТНЦ СО РАМНСибирский государственный медицинский университет МЗ РФНИИ фармакологии ТНЦ СО РАМНСибирский государственный медицинский университет МЗ РФСибирский государственный медицинский университет МЗ РФThere has been conducted a study of morphofunctional ovary changes at monopolar coagulation using histological, histochemical and ultra-microscopic techniques, and there have been evaluated hemorheologic factors and state of lipid peroxidation system (LPS) in postsurgical period. It has been proved that electrocoagulation stimulates the follicle growth for a short time but damages the generative and endocrine ovary apparatus and causes evident hemodynamic changes in perifocal zone. At the same time the raise of blood viscosity and erythrocyte aggregation and LPS activation are occurring. Possessing hemorheologic and antioxidant properties ascovertin produces a protective effect on generative ovary apparatus and microcirculation in it. 48 women after laparoscopic operations on ovaries with the use of electrocoagulation have been examined prospectively. The women of the basic group took the diquertin and ascorbic acid complex prior to and after the surgery in addition to the basic therapy. There has been made an evaluation of LPS factors prior to and after the surgery, computed kymopertubation results and hormonic state in a 1 month after the surgery, frequency of pregnancy beginning. Prescription of diquertin and ascorbic acid complex under the developed procedure is pathogenetically reasonable, it allows to increase the quality of treatment after laparoscopic operations on ovaries and encourages the preservation of reproductive function of a female organism.https://bulletin.ssmu.ru/jour/article/view/3747ovariesmonopolar coagulationmorphologyhemorheologylpsascovertin
spellingShingle I. Yu. Bukharina
O. A. Tikhonovskaya
M. B. Plotnikov
M. S. Petrova
M. Yu. Maslov
Ye. S. Koschevets
S. V. Logvinov
Experimental and clinical ground of using of diquertin and ascorbic acid complex at monopolar ovary coagulation
Бюллетень сибирской медицины
ovaries
monopolar coagulation
morphology
hemorheology
lps
ascovertin
title Experimental and clinical ground of using of diquertin and ascorbic acid complex at monopolar ovary coagulation
title_full Experimental and clinical ground of using of diquertin and ascorbic acid complex at monopolar ovary coagulation
title_fullStr Experimental and clinical ground of using of diquertin and ascorbic acid complex at monopolar ovary coagulation
title_full_unstemmed Experimental and clinical ground of using of diquertin and ascorbic acid complex at monopolar ovary coagulation
title_short Experimental and clinical ground of using of diquertin and ascorbic acid complex at monopolar ovary coagulation
title_sort experimental and clinical ground of using of diquertin and ascorbic acid complex at monopolar ovary coagulation
topic ovaries
monopolar coagulation
morphology
hemorheology
lps
ascovertin
url https://bulletin.ssmu.ru/jour/article/view/3747
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AT oatikhonovskaya experimentalandclinicalgroundofusingofdiquertinandascorbicacidcomplexatmonopolarovarycoagulation
AT mbplotnikov experimentalandclinicalgroundofusingofdiquertinandascorbicacidcomplexatmonopolarovarycoagulation
AT mspetrova experimentalandclinicalgroundofusingofdiquertinandascorbicacidcomplexatmonopolarovarycoagulation
AT myumaslov experimentalandclinicalgroundofusingofdiquertinandascorbicacidcomplexatmonopolarovarycoagulation
AT yeskoschevets experimentalandclinicalgroundofusingofdiquertinandascorbicacidcomplexatmonopolarovarycoagulation
AT svlogvinov experimentalandclinicalgroundofusingofdiquertinandascorbicacidcomplexatmonopolarovarycoagulation