Activated receptors for peroxisomic proliferators. Its role in the atherosclerosis, obesity and high blood pressure.
The receptors activated by peroxisome proliferators are a family of factors of transcription that belong to the superfamily of the steroid receptors and include tree subtypes which are PPARá, PPAR©¬ and PPAR ã. These receptors join to direct hexameric repetitions in the form of heterodimers with the...
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| Format: | Article |
| Language: | Spanish |
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Centro Provincial de Información de Ciencias Médicas. Cienfuegos
2004-08-01
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| Series: | Medisur |
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| Online Access: | http://medisur.sld.cu/index.php/medisur/article/view/57 |
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| author | Mikhail Benet Rodríguez Yosvel Curbelo Pérez |
| author_facet | Mikhail Benet Rodríguez Yosvel Curbelo Pérez |
| author_sort | Mikhail Benet Rodríguez |
| collection | DOAJ |
| description | The receptors activated by peroxisome proliferators are a family of factors of transcription that belong to the superfamily of the steroid receptors and include tree subtypes which are PPARá, PPAR©¬ and PPAR ã. These receptors join to direct hexameric repetitions in the form of heterodimers with the retinoid receptor. PPAR receptors regulate the expressions of a great variety of genes that codify the proteins that are implied in the lipid metabolism, the energetic homeostasis, the cellular differentiation and the formation of tumours. This review describes the features, regulation and target genes of the PPAR receptor and the physiopathological and pharmacological implications of the regulation of the lipid and glucose metabolism, the energetic homeostasis ,hypertension and endothelial dysfunction.<span style="font-family: Calibri;"><strong></strong></span> |
| format | Article |
| id | doaj-art-2fd67d05a0f04325be696bcf5abcfccb |
| institution | Kabale University |
| issn | 1727-897X |
| language | Spanish |
| publishDate | 2004-08-01 |
| publisher | Centro Provincial de Información de Ciencias Médicas. Cienfuegos |
| record_format | Article |
| series | Medisur |
| spelling | doaj-art-2fd67d05a0f04325be696bcf5abcfccb2025-01-30T21:28:36ZspaCentro Provincial de Información de Ciencias Médicas. CienfuegosMedisur1727-897X2004-08-0122516257Activated receptors for peroxisomic proliferators. Its role in the atherosclerosis, obesity and high blood pressure.Mikhail Benet RodríguezYosvel Curbelo PérezThe receptors activated by peroxisome proliferators are a family of factors of transcription that belong to the superfamily of the steroid receptors and include tree subtypes which are PPARá, PPAR©¬ and PPAR ã. These receptors join to direct hexameric repetitions in the form of heterodimers with the retinoid receptor. PPAR receptors regulate the expressions of a great variety of genes that codify the proteins that are implied in the lipid metabolism, the energetic homeostasis, the cellular differentiation and the formation of tumours. This review describes the features, regulation and target genes of the PPAR receptor and the physiopathological and pharmacological implications of the regulation of the lipid and glucose metabolism, the energetic homeostasis ,hypertension and endothelial dysfunction.<span style="font-family: Calibri;"><strong></strong></span>http://medisur.sld.cu/index.php/medisur/article/view/57proliferadores de peroxisomosfactores de transcripciónreceptores de esteroidesmetabolismo |
| spellingShingle | Mikhail Benet Rodríguez Yosvel Curbelo Pérez Activated receptors for peroxisomic proliferators. Its role in the atherosclerosis, obesity and high blood pressure. Medisur proliferadores de peroxisomos factores de transcripción receptores de esteroides metabolismo |
| title | Activated receptors for peroxisomic proliferators. Its role in the atherosclerosis, obesity and high blood pressure. |
| title_full | Activated receptors for peroxisomic proliferators. Its role in the atherosclerosis, obesity and high blood pressure. |
| title_fullStr | Activated receptors for peroxisomic proliferators. Its role in the atherosclerosis, obesity and high blood pressure. |
| title_full_unstemmed | Activated receptors for peroxisomic proliferators. Its role in the atherosclerosis, obesity and high blood pressure. |
| title_short | Activated receptors for peroxisomic proliferators. Its role in the atherosclerosis, obesity and high blood pressure. |
| title_sort | activated receptors for peroxisomic proliferators its role in the atherosclerosis obesity and high blood pressure |
| topic | proliferadores de peroxisomos factores de transcripción receptores de esteroides metabolismo |
| url | http://medisur.sld.cu/index.php/medisur/article/view/57 |
| work_keys_str_mv | AT mikhailbenetrodriguez activatedreceptorsforperoxisomicproliferatorsitsroleintheatherosclerosisobesityandhighbloodpressure AT yosvelcurbeloperez activatedreceptorsforperoxisomicproliferatorsitsroleintheatherosclerosisobesityandhighbloodpressure |