Determination of Natamycin in Turkish Yoghurt
This study was aimed at developing RP-HPLC method for determination of natamycin in Turkish yoghurt. Chromatographic separation was achieved on a C8 column (150 mm × 4.6 mm × 5 µm) with a mobile phase of methanol : water : acetic acid (12 : 8 : 1 v/v/v), at 1 mL/min flow rate with a detection of 303...
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Format: | Article |
Language: | English |
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Wiley
2016-01-01
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Series: | International Journal of Analytical Chemistry |
Online Access: | http://dx.doi.org/10.1155/2016/8480963 |
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author | Dilek Bilgic Alkaya Ozlem Karalomlu |
author_facet | Dilek Bilgic Alkaya Ozlem Karalomlu |
author_sort | Dilek Bilgic Alkaya |
collection | DOAJ |
description | This study was aimed at developing RP-HPLC method for determination of natamycin in Turkish yoghurt. Chromatographic separation was achieved on a C8 column (150 mm × 4.6 mm × 5 µm) with a mobile phase of methanol : water : acetic acid (12 : 8 : 1 v/v/v), at 1 mL/min flow rate with a detection of 303 nm. Natamycin was spiked into handmade yoghurt samples and used for validation. The method has been fully validated according to ISO 9233-2, 2007 (IDF 140-2, 2007). It was successfully applied to determination of 28 different Turkish yoghurt products. Findings dealing with the presence of natamycin in cheese samples are presented. |
format | Article |
id | doaj-art-2fd1062e6e8e4ebb932ff1a270e4f0b5 |
institution | Kabale University |
issn | 1687-8760 1687-8779 |
language | English |
publishDate | 2016-01-01 |
publisher | Wiley |
record_format | Article |
series | International Journal of Analytical Chemistry |
spelling | doaj-art-2fd1062e6e8e4ebb932ff1a270e4f0b52025-02-03T05:48:16ZengWileyInternational Journal of Analytical Chemistry1687-87601687-87792016-01-01201610.1155/2016/84809638480963Determination of Natamycin in Turkish YoghurtDilek Bilgic Alkaya0Ozlem Karalomlu1Faculty of Pharmacy, Department of Analytical Chemistry, Marmara University, P.O. Box 34668, Haydarpasa, Istanbul, TurkeyFaculty of Pharmacy, Department of Analytical Chemistry, Marmara University, P.O. Box 34668, Haydarpasa, Istanbul, TurkeyThis study was aimed at developing RP-HPLC method for determination of natamycin in Turkish yoghurt. Chromatographic separation was achieved on a C8 column (150 mm × 4.6 mm × 5 µm) with a mobile phase of methanol : water : acetic acid (12 : 8 : 1 v/v/v), at 1 mL/min flow rate with a detection of 303 nm. Natamycin was spiked into handmade yoghurt samples and used for validation. The method has been fully validated according to ISO 9233-2, 2007 (IDF 140-2, 2007). It was successfully applied to determination of 28 different Turkish yoghurt products. Findings dealing with the presence of natamycin in cheese samples are presented.http://dx.doi.org/10.1155/2016/8480963 |
spellingShingle | Dilek Bilgic Alkaya Ozlem Karalomlu Determination of Natamycin in Turkish Yoghurt International Journal of Analytical Chemistry |
title | Determination of Natamycin in Turkish Yoghurt |
title_full | Determination of Natamycin in Turkish Yoghurt |
title_fullStr | Determination of Natamycin in Turkish Yoghurt |
title_full_unstemmed | Determination of Natamycin in Turkish Yoghurt |
title_short | Determination of Natamycin in Turkish Yoghurt |
title_sort | determination of natamycin in turkish yoghurt |
url | http://dx.doi.org/10.1155/2016/8480963 |
work_keys_str_mv | AT dilekbilgicalkaya determinationofnatamycininturkishyoghurt AT ozlemkaralomlu determinationofnatamycininturkishyoghurt |