Dynamic profiling of Cell-free DNA fragmentation uncovers postprandial metabolic and immune alterations

Dynamic profiling of Cell-free DNA fragmentation uncovers postprandial metabolic and immune alterations

Abstract Background Food intake affects body homeostasis and significantly changes circulating cell-free DNA (cfDNA). However, the source and elimination of postprandial cfDNA is difficult to trace, and it is unknown whether these changes can be revealed by cfDNA fragmentomics based on liquid biopsy...

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Bibliographic Details
Main Authors: Ziting Zhu, Tao Chen, Manting Zhang, Xiaodi Shi, Pan Yu, Jianai Liu, Xiuzhi Duan, Zhihua Tao, Xuchu Wang
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Human Genomics
Subjects:
Cell-free DNA
CfDNA fragmentation
Immune response
Metabolic process
Liquid biopsy
Postprandial effects
Online Access:https://doi.org/10.1186/s40246-025-00739-4
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