Stem Cells for Augmenting Tendon Repair
Tendon healing is fraught with complications such as reruptures and adhesion formation due to the formation of scar tissue at the injury site as opposed to the regeneration of native tissue. Stem cells are an attractive option in developing cell-based therapies to improve tendon healing. However, se...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2012-01-01
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| Series: | Stem Cells International |
| Online Access: | http://dx.doi.org/10.1155/2012/291431 |
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| _version_ | 1832552281961136128 |
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| author | Lawrence V. Gulotta Salma Chaudhury Daniel Wiznia |
| author_facet | Lawrence V. Gulotta Salma Chaudhury Daniel Wiznia |
| author_sort | Lawrence V. Gulotta |
| collection | DOAJ |
| description | Tendon healing is fraught with complications such as reruptures and adhesion formation due to the formation of scar tissue at the injury site as opposed to the regeneration of native tissue. Stem cells are an attractive option in developing cell-based therapies to improve tendon healing. However, several questions remain to be answered before stem cells can be used clinically. Specifically, the type of stem cell, the amount of cells, and the proper combination of growth factors or mechanical stimuli to induce differentiation all remain to be seen. This paper outlines the current literature on the use of stem cells for tendon augmentation. |
| format | Article |
| id | doaj-art-2fc3a576468245d7b913b32c5775e8fa |
| institution | Kabale University |
| issn | 1687-966X 1687-9678 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Stem Cells International |
| spelling | doaj-art-2fc3a576468245d7b913b32c5775e8fa2025-02-03T05:58:59ZengWileyStem Cells International1687-966X1687-96782012-01-01201210.1155/2012/291431291431Stem Cells for Augmenting Tendon RepairLawrence V. Gulotta0Salma Chaudhury1Daniel Wiznia2Sports Medicine and Shoulder Service, Hospital for Special Surgery, 535 E 70th Street, New York, NY 10021, USASports Medicine and Shoulder Service, Hospital for Special Surgery, 535 E 70th Street, New York, NY 10021, USASports Medicine and Shoulder Service, Hospital for Special Surgery, 535 E 70th Street, New York, NY 10021, USATendon healing is fraught with complications such as reruptures and adhesion formation due to the formation of scar tissue at the injury site as opposed to the regeneration of native tissue. Stem cells are an attractive option in developing cell-based therapies to improve tendon healing. However, several questions remain to be answered before stem cells can be used clinically. Specifically, the type of stem cell, the amount of cells, and the proper combination of growth factors or mechanical stimuli to induce differentiation all remain to be seen. This paper outlines the current literature on the use of stem cells for tendon augmentation.http://dx.doi.org/10.1155/2012/291431 |
| spellingShingle | Lawrence V. Gulotta Salma Chaudhury Daniel Wiznia Stem Cells for Augmenting Tendon Repair Stem Cells International |
| title | Stem Cells for Augmenting Tendon Repair |
| title_full | Stem Cells for Augmenting Tendon Repair |
| title_fullStr | Stem Cells for Augmenting Tendon Repair |
| title_full_unstemmed | Stem Cells for Augmenting Tendon Repair |
| title_short | Stem Cells for Augmenting Tendon Repair |
| title_sort | stem cells for augmenting tendon repair |
| url | http://dx.doi.org/10.1155/2012/291431 |
| work_keys_str_mv | AT lawrencevgulotta stemcellsforaugmentingtendonrepair AT salmachaudhury stemcellsforaugmentingtendonrepair AT danielwiznia stemcellsforaugmentingtendonrepair |