Primary Cutaneous Anaplastic Large Cell Lymphoma of the Oral Cavity Successfully Treated with Brentuximab Vedotin
Primary cutaneous anaplastic large cell lymphoma is a CD-30 positive lymphoproliferative disorder with good prognosis, usually treated with radiation therapy and surgery. Head, neck, and extremities are the most frequently involved sites. In this paper, we describe an unusual case of oral localizati...
Saved in:
Main Authors: | , , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2019-01-01
|
Series: | Case Reports in Hematology |
Online Access: | http://dx.doi.org/10.1155/2019/9651207 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
_version_ | 1832551596453527552 |
---|---|
author | Federico Meconi Roberto Secchi Raffaele Palmieri Sara Vaccarini Vito Mario Rapisarda Laura Giannì Fabiana Esposito Ida Provenzano Daniela Nasso Livio Pupo Maria Cantonetti |
author_facet | Federico Meconi Roberto Secchi Raffaele Palmieri Sara Vaccarini Vito Mario Rapisarda Laura Giannì Fabiana Esposito Ida Provenzano Daniela Nasso Livio Pupo Maria Cantonetti |
author_sort | Federico Meconi |
collection | DOAJ |
description | Primary cutaneous anaplastic large cell lymphoma is a CD-30 positive lymphoproliferative disorder with good prognosis, usually treated with radiation therapy and surgery. Head, neck, and extremities are the most frequently involved sites. In this paper, we describe an unusual case of oral localization, recurring after skin-involving radiotherapy, successfully treated with sixteen cycles of brentuximab vedotin. This could be a more effective approach with a less detrimental toll for treating these rare disorders. |
format | Article |
id | doaj-art-2fba72627ab945cc931ccd6aa4a8ef17 |
institution | Kabale University |
issn | 2090-6560 2090-6579 |
language | English |
publishDate | 2019-01-01 |
publisher | Wiley |
record_format | Article |
series | Case Reports in Hematology |
spelling | doaj-art-2fba72627ab945cc931ccd6aa4a8ef172025-02-03T06:01:07ZengWileyCase Reports in Hematology2090-65602090-65792019-01-01201910.1155/2019/96512079651207Primary Cutaneous Anaplastic Large Cell Lymphoma of the Oral Cavity Successfully Treated with Brentuximab VedotinFederico Meconi0Roberto Secchi1Raffaele Palmieri2Sara Vaccarini3Vito Mario Rapisarda4Laura Giannì5Fabiana Esposito6Ida Provenzano7Daniela Nasso8Livio Pupo9Maria Cantonetti10Department of Biomedicine and Prevention, Haematology Division, University of Tor Vergata, Viale Oxford 81, Rome, ItalyDepartment of Biomedicine and Prevention, Haematology Division, University of Tor Vergata, Viale Oxford 81, Rome, ItalyDepartment of Biomedicine and Prevention, Haematology Division, University of Tor Vergata, Viale Oxford 81, Rome, ItalyDepartment of Biomedicine and Prevention, Haematology Division, University of Tor Vergata, Viale Oxford 81, Rome, ItalyDepartment of Biomedicine and Prevention, Haematology Division, University of Tor Vergata, Viale Oxford 81, Rome, ItalyDepartment of Biomedicine and Prevention, Haematology Division, University of Tor Vergata, Viale Oxford 81, Rome, ItalyDepartment of Biomedicine and Prevention, Haematology Division, University of Tor Vergata, Viale Oxford 81, Rome, ItalyDepartment of Biomedicine and Prevention, Haematology Division, University of Tor Vergata, Viale Oxford 81, Rome, ItalyDepartment of Biomedicine and Prevention, Haematology Division, University of Tor Vergata, Viale Oxford 81, Rome, ItalyDepartment of Biomedicine and Prevention, Haematology Division, University of Tor Vergata, Viale Oxford 81, Rome, ItalyDepartment of Biomedicine and Prevention, Haematology Division, University of Tor Vergata, Viale Oxford 81, Rome, ItalyPrimary cutaneous anaplastic large cell lymphoma is a CD-30 positive lymphoproliferative disorder with good prognosis, usually treated with radiation therapy and surgery. Head, neck, and extremities are the most frequently involved sites. In this paper, we describe an unusual case of oral localization, recurring after skin-involving radiotherapy, successfully treated with sixteen cycles of brentuximab vedotin. This could be a more effective approach with a less detrimental toll for treating these rare disorders.http://dx.doi.org/10.1155/2019/9651207 |
spellingShingle | Federico Meconi Roberto Secchi Raffaele Palmieri Sara Vaccarini Vito Mario Rapisarda Laura Giannì Fabiana Esposito Ida Provenzano Daniela Nasso Livio Pupo Maria Cantonetti Primary Cutaneous Anaplastic Large Cell Lymphoma of the Oral Cavity Successfully Treated with Brentuximab Vedotin Case Reports in Hematology |
title | Primary Cutaneous Anaplastic Large Cell Lymphoma of the Oral Cavity Successfully Treated with Brentuximab Vedotin |
title_full | Primary Cutaneous Anaplastic Large Cell Lymphoma of the Oral Cavity Successfully Treated with Brentuximab Vedotin |
title_fullStr | Primary Cutaneous Anaplastic Large Cell Lymphoma of the Oral Cavity Successfully Treated with Brentuximab Vedotin |
title_full_unstemmed | Primary Cutaneous Anaplastic Large Cell Lymphoma of the Oral Cavity Successfully Treated with Brentuximab Vedotin |
title_short | Primary Cutaneous Anaplastic Large Cell Lymphoma of the Oral Cavity Successfully Treated with Brentuximab Vedotin |
title_sort | primary cutaneous anaplastic large cell lymphoma of the oral cavity successfully treated with brentuximab vedotin |
url | http://dx.doi.org/10.1155/2019/9651207 |
work_keys_str_mv | AT federicomeconi primarycutaneousanaplasticlargecelllymphomaoftheoralcavitysuccessfullytreatedwithbrentuximabvedotin AT robertosecchi primarycutaneousanaplasticlargecelllymphomaoftheoralcavitysuccessfullytreatedwithbrentuximabvedotin AT raffaelepalmieri primarycutaneousanaplasticlargecelllymphomaoftheoralcavitysuccessfullytreatedwithbrentuximabvedotin AT saravaccarini primarycutaneousanaplasticlargecelllymphomaoftheoralcavitysuccessfullytreatedwithbrentuximabvedotin AT vitomariorapisarda primarycutaneousanaplasticlargecelllymphomaoftheoralcavitysuccessfullytreatedwithbrentuximabvedotin AT lauragianni primarycutaneousanaplasticlargecelllymphomaoftheoralcavitysuccessfullytreatedwithbrentuximabvedotin AT fabianaesposito primarycutaneousanaplasticlargecelllymphomaoftheoralcavitysuccessfullytreatedwithbrentuximabvedotin AT idaprovenzano primarycutaneousanaplasticlargecelllymphomaoftheoralcavitysuccessfullytreatedwithbrentuximabvedotin AT danielanasso primarycutaneousanaplasticlargecelllymphomaoftheoralcavitysuccessfullytreatedwithbrentuximabvedotin AT liviopupo primarycutaneousanaplasticlargecelllymphomaoftheoralcavitysuccessfullytreatedwithbrentuximabvedotin AT mariacantonetti primarycutaneousanaplasticlargecelllymphomaoftheoralcavitysuccessfullytreatedwithbrentuximabvedotin |