Primary Cutaneous Anaplastic Large Cell Lymphoma of the Oral Cavity Successfully Treated with Brentuximab Vedotin

Primary cutaneous anaplastic large cell lymphoma is a CD-30 positive lymphoproliferative disorder with good prognosis, usually treated with radiation therapy and surgery. Head, neck, and extremities are the most frequently involved sites. In this paper, we describe an unusual case of oral localizati...

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Main Authors: Federico Meconi, Roberto Secchi, Raffaele Palmieri, Sara Vaccarini, Vito Mario Rapisarda, Laura Giannì, Fabiana Esposito, Ida Provenzano, Daniela Nasso, Livio Pupo, Maria Cantonetti
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Case Reports in Hematology
Online Access:http://dx.doi.org/10.1155/2019/9651207
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author Federico Meconi
Roberto Secchi
Raffaele Palmieri
Sara Vaccarini
Vito Mario Rapisarda
Laura Giannì
Fabiana Esposito
Ida Provenzano
Daniela Nasso
Livio Pupo
Maria Cantonetti
author_facet Federico Meconi
Roberto Secchi
Raffaele Palmieri
Sara Vaccarini
Vito Mario Rapisarda
Laura Giannì
Fabiana Esposito
Ida Provenzano
Daniela Nasso
Livio Pupo
Maria Cantonetti
author_sort Federico Meconi
collection DOAJ
description Primary cutaneous anaplastic large cell lymphoma is a CD-30 positive lymphoproliferative disorder with good prognosis, usually treated with radiation therapy and surgery. Head, neck, and extremities are the most frequently involved sites. In this paper, we describe an unusual case of oral localization, recurring after skin-involving radiotherapy, successfully treated with sixteen cycles of brentuximab vedotin. This could be a more effective approach with a less detrimental toll for treating these rare disorders.
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institution Kabale University
issn 2090-6560
2090-6579
language English
publishDate 2019-01-01
publisher Wiley
record_format Article
series Case Reports in Hematology
spelling doaj-art-2fba72627ab945cc931ccd6aa4a8ef172025-02-03T06:01:07ZengWileyCase Reports in Hematology2090-65602090-65792019-01-01201910.1155/2019/96512079651207Primary Cutaneous Anaplastic Large Cell Lymphoma of the Oral Cavity Successfully Treated with Brentuximab VedotinFederico Meconi0Roberto Secchi1Raffaele Palmieri2Sara Vaccarini3Vito Mario Rapisarda4Laura Giannì5Fabiana Esposito6Ida Provenzano7Daniela Nasso8Livio Pupo9Maria Cantonetti10Department of Biomedicine and Prevention, Haematology Division, University of Tor Vergata, Viale Oxford 81, Rome, ItalyDepartment of Biomedicine and Prevention, Haematology Division, University of Tor Vergata, Viale Oxford 81, Rome, ItalyDepartment of Biomedicine and Prevention, Haematology Division, University of Tor Vergata, Viale Oxford 81, Rome, ItalyDepartment of Biomedicine and Prevention, Haematology Division, University of Tor Vergata, Viale Oxford 81, Rome, ItalyDepartment of Biomedicine and Prevention, Haematology Division, University of Tor Vergata, Viale Oxford 81, Rome, ItalyDepartment of Biomedicine and Prevention, Haematology Division, University of Tor Vergata, Viale Oxford 81, Rome, ItalyDepartment of Biomedicine and Prevention, Haematology Division, University of Tor Vergata, Viale Oxford 81, Rome, ItalyDepartment of Biomedicine and Prevention, Haematology Division, University of Tor Vergata, Viale Oxford 81, Rome, ItalyDepartment of Biomedicine and Prevention, Haematology Division, University of Tor Vergata, Viale Oxford 81, Rome, ItalyDepartment of Biomedicine and Prevention, Haematology Division, University of Tor Vergata, Viale Oxford 81, Rome, ItalyDepartment of Biomedicine and Prevention, Haematology Division, University of Tor Vergata, Viale Oxford 81, Rome, ItalyPrimary cutaneous anaplastic large cell lymphoma is a CD-30 positive lymphoproliferative disorder with good prognosis, usually treated with radiation therapy and surgery. Head, neck, and extremities are the most frequently involved sites. In this paper, we describe an unusual case of oral localization, recurring after skin-involving radiotherapy, successfully treated with sixteen cycles of brentuximab vedotin. This could be a more effective approach with a less detrimental toll for treating these rare disorders.http://dx.doi.org/10.1155/2019/9651207
spellingShingle Federico Meconi
Roberto Secchi
Raffaele Palmieri
Sara Vaccarini
Vito Mario Rapisarda
Laura Giannì
Fabiana Esposito
Ida Provenzano
Daniela Nasso
Livio Pupo
Maria Cantonetti
Primary Cutaneous Anaplastic Large Cell Lymphoma of the Oral Cavity Successfully Treated with Brentuximab Vedotin
Case Reports in Hematology
title Primary Cutaneous Anaplastic Large Cell Lymphoma of the Oral Cavity Successfully Treated with Brentuximab Vedotin
title_full Primary Cutaneous Anaplastic Large Cell Lymphoma of the Oral Cavity Successfully Treated with Brentuximab Vedotin
title_fullStr Primary Cutaneous Anaplastic Large Cell Lymphoma of the Oral Cavity Successfully Treated with Brentuximab Vedotin
title_full_unstemmed Primary Cutaneous Anaplastic Large Cell Lymphoma of the Oral Cavity Successfully Treated with Brentuximab Vedotin
title_short Primary Cutaneous Anaplastic Large Cell Lymphoma of the Oral Cavity Successfully Treated with Brentuximab Vedotin
title_sort primary cutaneous anaplastic large cell lymphoma of the oral cavity successfully treated with brentuximab vedotin
url http://dx.doi.org/10.1155/2019/9651207
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