Double trouble: cytosolic and nuclear IKKα in cancer

Double trouble: cytosolic and nuclear IKKα in cancer

IκB kinase alpha (IKKα) is a serine/threonine kinase originally known for its role in nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) signalling, which integrates inflammatory processes and cancer. IKKα can function within the IKK complex in canonical NF-κB signalling, alongsi...

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Bibliographic Details
Main Authors:	Kirsty Tinto, Margaret Cunningham, Robin Plevin
Format:	Article
Language:	English
Published:	The Royal Society 2025-08-01
Series:	Open Biology
Subjects:	cytosolic nuclear IKKα cancer NF-κB
Online Access:	https://royalsocietypublishing.org/doi/10.1098/rsob.240375
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