Primitive Neuroectodermal Tumor of the Liver: A Case Report
Primary liver sarcomas represent a rare group of neoplasias, with angiosarcoma being the most common histological type. Primitive neuroectodermal tumor (PNET) represents a high malignant neoplasia that usually affects the central nervous system and soft tissues. An 18-year-old male patient was admit...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2011-01-01
|
| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2011/748194 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832564674410840064 |
|---|---|
| author | Eduardo Cambruzzi Enilde Eloena Guerra Hamilton Cardoso Hilgert Herbert Jorge Schmitz Vinícius Lopes Silva Daniel Marini Milani Ricardo Pedrini Cruz Raul Pruinelli |
| author_facet | Eduardo Cambruzzi Enilde Eloena Guerra Hamilton Cardoso Hilgert Herbert Jorge Schmitz Vinícius Lopes Silva Daniel Marini Milani Ricardo Pedrini Cruz Raul Pruinelli |
| author_sort | Eduardo Cambruzzi |
| collection | DOAJ |
| description | Primary liver sarcomas represent a rare group of neoplasias, with angiosarcoma being the most common histological type. Primitive neuroectodermal tumor (PNET) represents a high malignant neoplasia that usually affects the central nervous system and soft tissues. An 18-year-old male patient was admitted with clinical complains of pain in the right upper abdominal quadrant. The clinical evaluation revealed a solid mass in the right hepatic lobe. On the gross examination of the resected liver specimen, the right lobe of the liver was replaced by a yellow-red solid mass measuring 21 cm in its largest dimension. On the histopathology, a tumor composed of small round blue cells with little cytoplasm and round nuclei was identified. The lesion revealed positive immunoexpression for vimentin and CD99 and negative immunostaining for desmin, CD45, cytokeratin, and neuroblastoma protein, suggesting, then, the diagnosis of PNET. Although it is an unusual tumor, it should be considered in the differential diagnosis of liver masses, especially in young patients. |
| format | Article |
| id | doaj-art-2f7a6dc14ee049ae9ad329f90b02b350 |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-2f7a6dc14ee049ae9ad329f90b02b3502025-02-03T01:10:24ZengWileyCase Reports in Medicine1687-96271687-96352011-01-01201110.1155/2011/748194748194Primitive Neuroectodermal Tumor of the Liver: A Case ReportEduardo Cambruzzi0Enilde Eloena Guerra1Hamilton Cardoso Hilgert2Herbert Jorge Schmitz3Vinícius Lopes Silva4Daniel Marini Milani5Ricardo Pedrini Cruz6Raul Pruinelli7Department of Pathology, Nossa Senhora da Conceição Hospital, Porto Alegre, Rio Grande do Sul, BrazilDepartment of Surgery, Nossa Senhora da Conceição Hospital, Porto Alegre, Rio Grande do Sul, BrazilDepartment of Surgery, Nossa Senhora da Conceição Hospital, Porto Alegre, Rio Grande do Sul, BrazilDepartment of Surgery, Nossa Senhora da Conceição Hospital, Porto Alegre, Rio Grande do Sul, BrazilDepartment of Surgery, Nossa Senhora da Conceição Hospital, Porto Alegre, Rio Grande do Sul, BrazilDepartment of Surgery, Nossa Senhora da Conceição Hospital, Porto Alegre, Rio Grande do Sul, BrazilDepartment of Surgery, Nossa Senhora da Conceição Hospital, Porto Alegre, Rio Grande do Sul, BrazilDepartment of Surgery, Nossa Senhora da Conceição Hospital, Porto Alegre, Rio Grande do Sul, BrazilPrimary liver sarcomas represent a rare group of neoplasias, with angiosarcoma being the most common histological type. Primitive neuroectodermal tumor (PNET) represents a high malignant neoplasia that usually affects the central nervous system and soft tissues. An 18-year-old male patient was admitted with clinical complains of pain in the right upper abdominal quadrant. The clinical evaluation revealed a solid mass in the right hepatic lobe. On the gross examination of the resected liver specimen, the right lobe of the liver was replaced by a yellow-red solid mass measuring 21 cm in its largest dimension. On the histopathology, a tumor composed of small round blue cells with little cytoplasm and round nuclei was identified. The lesion revealed positive immunoexpression for vimentin and CD99 and negative immunostaining for desmin, CD45, cytokeratin, and neuroblastoma protein, suggesting, then, the diagnosis of PNET. Although it is an unusual tumor, it should be considered in the differential diagnosis of liver masses, especially in young patients.http://dx.doi.org/10.1155/2011/748194 |
| spellingShingle | Eduardo Cambruzzi Enilde Eloena Guerra Hamilton Cardoso Hilgert Herbert Jorge Schmitz Vinícius Lopes Silva Daniel Marini Milani Ricardo Pedrini Cruz Raul Pruinelli Primitive Neuroectodermal Tumor of the Liver: A Case Report Case Reports in Medicine |
| title | Primitive Neuroectodermal Tumor of the Liver: A Case Report |
| title_full | Primitive Neuroectodermal Tumor of the Liver: A Case Report |
| title_fullStr | Primitive Neuroectodermal Tumor of the Liver: A Case Report |
| title_full_unstemmed | Primitive Neuroectodermal Tumor of the Liver: A Case Report |
| title_short | Primitive Neuroectodermal Tumor of the Liver: A Case Report |
| title_sort | primitive neuroectodermal tumor of the liver a case report |
| url | http://dx.doi.org/10.1155/2011/748194 |
| work_keys_str_mv | AT eduardocambruzzi primitiveneuroectodermaltumoroftheliveracasereport AT enildeeloenaguerra primitiveneuroectodermaltumoroftheliveracasereport AT hamiltoncardosohilgert primitiveneuroectodermaltumoroftheliveracasereport AT herbertjorgeschmitz primitiveneuroectodermaltumoroftheliveracasereport AT viniciuslopessilva primitiveneuroectodermaltumoroftheliveracasereport AT danielmarinimilani primitiveneuroectodermaltumoroftheliveracasereport AT ricardopedrinicruz primitiveneuroectodermaltumoroftheliveracasereport AT raulpruinelli primitiveneuroectodermaltumoroftheliveracasereport |