Factors influencing performance of internet-based biosurveillance systems used in epidemic intelligence for early detection of infectious diseases outbreaks.

<h4>Background</h4>Internet-based biosurveillance systems have been developed to detect health threats using information available on the Internet, but system performance has not been assessed relative to end-user needs and perspectives.<h4>Method and findings</h4>Infectious...

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Main Authors: Philippe Barboza, Laetitia Vaillant, Yann Le Strat, David M Hartley, Noele P Nelson, Abla Mawudeku, Lawrence C Madoff, Jens P Linge, Nigel Collier, John S Brownstein, Pascal Astagneau
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0090536&type=printable
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author Philippe Barboza
Laetitia Vaillant
Yann Le Strat
David M Hartley
Noele P Nelson
Abla Mawudeku
Lawrence C Madoff
Jens P Linge
Nigel Collier
John S Brownstein
Pascal Astagneau
author_facet Philippe Barboza
Laetitia Vaillant
Yann Le Strat
David M Hartley
Noele P Nelson
Abla Mawudeku
Lawrence C Madoff
Jens P Linge
Nigel Collier
John S Brownstein
Pascal Astagneau
author_sort Philippe Barboza
collection DOAJ
description <h4>Background</h4>Internet-based biosurveillance systems have been developed to detect health threats using information available on the Internet, but system performance has not been assessed relative to end-user needs and perspectives.<h4>Method and findings</h4>Infectious disease events from the French Institute for Public Health Surveillance (InVS) weekly international epidemiological bulletin published in 2010 were used to construct the gold-standard official dataset. Data from six biosurveillance systems were used to detect raw signals (infectious disease events from informal Internet sources): Argus, BioCaster, GPHIN, HealthMap, MedISys and ProMED-mail. Crude detection rates (C-DR), crude sensitivity rates (C-Se) and intrinsic sensitivity rates (I-Se) were calculated from multivariable regressions to evaluate the systems' performance (events detected compared to the gold-standard) 472 raw signals (Internet disease reports) related to the 86 events included in the gold-standard data set were retrieved from the six systems. 84 events were detected before their publication in the gold-standard. The type of sources utilised by the systems varied significantly (p<0001). I-Se varied significantly from 43% to 71% (p=0001) whereas other indicators were similar (C-DR: p=020; C-Se, p=013). I-Se was significantly associated with individual systems, types of system, languages, regions of occurrence, and types of infectious disease. Conversely, no statistical difference of C-DR was observed after adjustment for other variables.<h4>Conclusion</h4>Although differences could result from a biosurveillance system's conceptual design, findings suggest that the combined expertise amongst systems enhances early detection performance for detection of infectious diseases. While all systems showed similar early detection performance, systems including human moderation were found to have a 53% higher I-Se (p=00001) after adjustment for other variables. Overall, the use of moderation, sources, languages, regions of occurrence, and types of cases were found to influence system performance.
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spelling doaj-art-2f7403c7b1e442f1b426daf4d2563c5b2025-08-20T02:15:19ZengPublic Library of Science (PLoS)PLoS ONE1932-62032014-01-0193e9053610.1371/journal.pone.0090536Factors influencing performance of internet-based biosurveillance systems used in epidemic intelligence for early detection of infectious diseases outbreaks.Philippe BarbozaLaetitia VaillantYann Le StratDavid M HartleyNoele P NelsonAbla MawudekuLawrence C MadoffJens P LingeNigel CollierJohn S BrownsteinPascal Astagneau<h4>Background</h4>Internet-based biosurveillance systems have been developed to detect health threats using information available on the Internet, but system performance has not been assessed relative to end-user needs and perspectives.<h4>Method and findings</h4>Infectious disease events from the French Institute for Public Health Surveillance (InVS) weekly international epidemiological bulletin published in 2010 were used to construct the gold-standard official dataset. Data from six biosurveillance systems were used to detect raw signals (infectious disease events from informal Internet sources): Argus, BioCaster, GPHIN, HealthMap, MedISys and ProMED-mail. Crude detection rates (C-DR), crude sensitivity rates (C-Se) and intrinsic sensitivity rates (I-Se) were calculated from multivariable regressions to evaluate the systems' performance (events detected compared to the gold-standard) 472 raw signals (Internet disease reports) related to the 86 events included in the gold-standard data set were retrieved from the six systems. 84 events were detected before their publication in the gold-standard. The type of sources utilised by the systems varied significantly (p<0001). I-Se varied significantly from 43% to 71% (p=0001) whereas other indicators were similar (C-DR: p=020; C-Se, p=013). I-Se was significantly associated with individual systems, types of system, languages, regions of occurrence, and types of infectious disease. Conversely, no statistical difference of C-DR was observed after adjustment for other variables.<h4>Conclusion</h4>Although differences could result from a biosurveillance system's conceptual design, findings suggest that the combined expertise amongst systems enhances early detection performance for detection of infectious diseases. While all systems showed similar early detection performance, systems including human moderation were found to have a 53% higher I-Se (p=00001) after adjustment for other variables. Overall, the use of moderation, sources, languages, regions of occurrence, and types of cases were found to influence system performance.https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0090536&type=printable
spellingShingle Philippe Barboza
Laetitia Vaillant
Yann Le Strat
David M Hartley
Noele P Nelson
Abla Mawudeku
Lawrence C Madoff
Jens P Linge
Nigel Collier
John S Brownstein
Pascal Astagneau
Factors influencing performance of internet-based biosurveillance systems used in epidemic intelligence for early detection of infectious diseases outbreaks.
PLoS ONE
title Factors influencing performance of internet-based biosurveillance systems used in epidemic intelligence for early detection of infectious diseases outbreaks.
title_full Factors influencing performance of internet-based biosurveillance systems used in epidemic intelligence for early detection of infectious diseases outbreaks.
title_fullStr Factors influencing performance of internet-based biosurveillance systems used in epidemic intelligence for early detection of infectious diseases outbreaks.
title_full_unstemmed Factors influencing performance of internet-based biosurveillance systems used in epidemic intelligence for early detection of infectious diseases outbreaks.
title_short Factors influencing performance of internet-based biosurveillance systems used in epidemic intelligence for early detection of infectious diseases outbreaks.
title_sort factors influencing performance of internet based biosurveillance systems used in epidemic intelligence for early detection of infectious diseases outbreaks
url https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0090536&type=printable
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