Whole-genome sequence of bioactive streptomycete derived from mangrove forest in Malaysia, Streptomyces sp. MUSC 14
The contribution of streptomycetes to human health is undeniably important and significant, given that these filamentous microbes can produce interesting compounds that can be used to cure deadly infections and even cancer. Isolated from the east coast of Peninsular Malaysia, Streptomyces sp. MUSC...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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HH Publisher
2021-04-01
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| Series: | Progress in Microbes and Molecular Biology |
| Online Access: | https://journals.hh-publisher.com/index.php/pmmb/article/view/461 |
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| _version_ | 1832541393369694208 |
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| author | Hooi-Leng Ser Loh Teng-Hern Tan Wen-Si Tan Wai-Fong Yin Kok-Gan Chan |
| author_facet | Hooi-Leng Ser Loh Teng-Hern Tan Wen-Si Tan Wai-Fong Yin Kok-Gan Chan |
| author_sort | Hooi-Leng Ser |
| collection | DOAJ |
| description |
The contribution of streptomycetes to human health is undeniably important and significant, given that these filamentous microbes can produce interesting compounds that can be used to cure deadly infections and even cancer. Isolated from the east coast of Peninsular Malaysia, Streptomyces sp. MUSC 14 has shown significant antioxidant capacity. The current study explores the genomic potential of MUSC 14 via a genome mining approach. The genome size of MUSC 14 is 10,274,825 bp with G + C content of 71.3 %. AntiSMASH analysis revealed a total of nine biosynthetic gene clusters (with more than 80 % similarities to known gene clusters). This information serves as an important foundation for subsequent studies, particularly the purification and isolation of bioactive compounds by genetic manipulation techniques.
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| format | Article |
| id | doaj-art-2f508f41a9df4dd699d4c9460cca487d |
| institution | Kabale University |
| issn | 2637-1049 |
| language | English |
| publishDate | 2021-04-01 |
| publisher | HH Publisher |
| record_format | Article |
| series | Progress in Microbes and Molecular Biology |
| spelling | doaj-art-2f508f41a9df4dd699d4c9460cca487d2025-02-04T08:36:56ZengHH PublisherProgress in Microbes and Molecular Biology2637-10492021-04-014110.36877/pmmb.a0000195Whole-genome sequence of bioactive streptomycete derived from mangrove forest in Malaysia, Streptomyces sp. MUSC 14Hooi-Leng SerLoh Teng-Hern TanWen-Si TanWai-Fong YinKok-Gan Chan The contribution of streptomycetes to human health is undeniably important and significant, given that these filamentous microbes can produce interesting compounds that can be used to cure deadly infections and even cancer. Isolated from the east coast of Peninsular Malaysia, Streptomyces sp. MUSC 14 has shown significant antioxidant capacity. The current study explores the genomic potential of MUSC 14 via a genome mining approach. The genome size of MUSC 14 is 10,274,825 bp with G + C content of 71.3 %. AntiSMASH analysis revealed a total of nine biosynthetic gene clusters (with more than 80 % similarities to known gene clusters). This information serves as an important foundation for subsequent studies, particularly the purification and isolation of bioactive compounds by genetic manipulation techniques. https://journals.hh-publisher.com/index.php/pmmb/article/view/461 |
| spellingShingle | Hooi-Leng Ser Loh Teng-Hern Tan Wen-Si Tan Wai-Fong Yin Kok-Gan Chan Whole-genome sequence of bioactive streptomycete derived from mangrove forest in Malaysia, Streptomyces sp. MUSC 14 Progress in Microbes and Molecular Biology |
| title | Whole-genome sequence of bioactive streptomycete derived from mangrove forest in Malaysia, Streptomyces sp. MUSC 14 |
| title_full | Whole-genome sequence of bioactive streptomycete derived from mangrove forest in Malaysia, Streptomyces sp. MUSC 14 |
| title_fullStr | Whole-genome sequence of bioactive streptomycete derived from mangrove forest in Malaysia, Streptomyces sp. MUSC 14 |
| title_full_unstemmed | Whole-genome sequence of bioactive streptomycete derived from mangrove forest in Malaysia, Streptomyces sp. MUSC 14 |
| title_short | Whole-genome sequence of bioactive streptomycete derived from mangrove forest in Malaysia, Streptomyces sp. MUSC 14 |
| title_sort | whole genome sequence of bioactive streptomycete derived from mangrove forest in malaysia streptomyces sp musc 14 |
| url | https://journals.hh-publisher.com/index.php/pmmb/article/view/461 |
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