Splenic Abscess: An Uncommon Entity with Potentially Life-Threatening Evolution

Background/Purpose. Splenic abscess is rare with potentially life-threatening evolution. The aim of this study is to review the clinical features, microbiological etiologies, treatment, and outcomes of patients with splenic abscess. Methods. We reviewed the admitted patients with suspected splenic a...

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Main Authors: Mei-Chun Lee, Chun-Ming Lee
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Canadian Journal of Infectious Diseases and Medical Microbiology
Online Access:http://dx.doi.org/10.1155/2018/8610657
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author Mei-Chun Lee
Chun-Ming Lee
author_facet Mei-Chun Lee
Chun-Ming Lee
author_sort Mei-Chun Lee
collection DOAJ
description Background/Purpose. Splenic abscess is rare with potentially life-threatening evolution. The aim of this study is to review the clinical features, microbiological etiologies, treatment, and outcomes of patients with splenic abscess. Methods. We reviewed the admitted patients with suspected splenic abscess and made the diagnosis of splenic abscess. The clinical characteristics, underlying diseases, treatment course, organism spectra, abscess number and size, therapeutic methods, and clinical outcome at a tertiary medical center in Taiwan over a period of 5 years were analyzed. Results. Of 16 patients with splenic abscess, the male to female ratio was 1 : 1. Common presentations were fever (11 patients, 68.7%), diffuse abdominal pain (6 patients, 37.5%), left upper quadrant pain or tenderness (6 patients, 37.5%), and left-sided pleural effusions (8 patients, 50%). Antimicrobial therapy was administered in all patients. Fourteen (87.5%) patients recovered under medical treatment. One (6.2%) patient underwent splenectomy, four (25%) patients performed percutaneous drainage of their splenic abscess, and 11 (68.7%) patients received antimicrobial therapy alone. Conclusion. We noted that mortality may be more related to patients with underlying immunodeficiency. Patients with splenic abscesses receiving antimicrobial therapy alone were in a relatively high proportion and got a good prognosis especially in patients with small and multiple abscesses.
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spelling doaj-art-2f447f803ea84c158d49c26bacc8da8f2025-02-03T05:46:49ZengWileyCanadian Journal of Infectious Diseases and Medical Microbiology1712-95321918-14932018-01-01201810.1155/2018/86106578610657Splenic Abscess: An Uncommon Entity with Potentially Life-Threatening EvolutionMei-Chun Lee0Chun-Ming Lee1Department of Pharmacy, MacKay Memorial Hospital, Taipei, TaiwanMackay Junior College of Medicine, Nursing and Management, Taipei, TaiwanBackground/Purpose. Splenic abscess is rare with potentially life-threatening evolution. The aim of this study is to review the clinical features, microbiological etiologies, treatment, and outcomes of patients with splenic abscess. Methods. We reviewed the admitted patients with suspected splenic abscess and made the diagnosis of splenic abscess. The clinical characteristics, underlying diseases, treatment course, organism spectra, abscess number and size, therapeutic methods, and clinical outcome at a tertiary medical center in Taiwan over a period of 5 years were analyzed. Results. Of 16 patients with splenic abscess, the male to female ratio was 1 : 1. Common presentations were fever (11 patients, 68.7%), diffuse abdominal pain (6 patients, 37.5%), left upper quadrant pain or tenderness (6 patients, 37.5%), and left-sided pleural effusions (8 patients, 50%). Antimicrobial therapy was administered in all patients. Fourteen (87.5%) patients recovered under medical treatment. One (6.2%) patient underwent splenectomy, four (25%) patients performed percutaneous drainage of their splenic abscess, and 11 (68.7%) patients received antimicrobial therapy alone. Conclusion. We noted that mortality may be more related to patients with underlying immunodeficiency. Patients with splenic abscesses receiving antimicrobial therapy alone were in a relatively high proportion and got a good prognosis especially in patients with small and multiple abscesses.http://dx.doi.org/10.1155/2018/8610657
spellingShingle Mei-Chun Lee
Chun-Ming Lee
Splenic Abscess: An Uncommon Entity with Potentially Life-Threatening Evolution
Canadian Journal of Infectious Diseases and Medical Microbiology
title Splenic Abscess: An Uncommon Entity with Potentially Life-Threatening Evolution
title_full Splenic Abscess: An Uncommon Entity with Potentially Life-Threatening Evolution
title_fullStr Splenic Abscess: An Uncommon Entity with Potentially Life-Threatening Evolution
title_full_unstemmed Splenic Abscess: An Uncommon Entity with Potentially Life-Threatening Evolution
title_short Splenic Abscess: An Uncommon Entity with Potentially Life-Threatening Evolution
title_sort splenic abscess an uncommon entity with potentially life threatening evolution
url http://dx.doi.org/10.1155/2018/8610657
work_keys_str_mv AT meichunlee splenicabscessanuncommonentitywithpotentiallylifethreateningevolution
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