Two-Person Technique of Peroral Endoscopic Myotomy for Achalasia with an Advanced Endoscopist and a Thoracic Surgeon: Initial Experience

Background and Aims. We initiated peroral endoscopic myotomy (POEM) utilizing a two-person technique with combination of an advanced endoscopist and a thoracic surgeon with complementary skills. Our aim was to determine the feasibility and outcomes in initial 20 patients. Methods. In this observatio...

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Main Authors: Madhusudhan R. Sanaka, Ramprasad Jegadeesan, Prashanthi N. Thota, Udayakumar Navaneethan, Rocio Lopez, Sudish C. Murthy, Siva Raja
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Canadian Journal of Gastroenterology and Hepatology
Online Access:http://dx.doi.org/10.1155/2016/2656101
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author Madhusudhan R. Sanaka
Ramprasad Jegadeesan
Prashanthi N. Thota
Udayakumar Navaneethan
Rocio Lopez
Sudish C. Murthy
Siva Raja
author_facet Madhusudhan R. Sanaka
Ramprasad Jegadeesan
Prashanthi N. Thota
Udayakumar Navaneethan
Rocio Lopez
Sudish C. Murthy
Siva Raja
author_sort Madhusudhan R. Sanaka
collection DOAJ
description Background and Aims. We initiated peroral endoscopic myotomy (POEM) utilizing a two-person technique with combination of an advanced endoscopist and a thoracic surgeon with complementary skills. Our aim was to determine the feasibility and outcomes in initial 20 patients. Methods. In this observational study, main outcomes measured were therapeutic success in relieving symptoms (Eckardt score < 3), decrease in lower esophageal sphincter (LES) pressures, improvement in emptying on timed barium esophagogram (TBE), and complications. Results. POEM was successful in all 20 patients with a mean operative time of 140.1+32.9 minutes. Eckardt symptom scores decreased significantly at two-month follow-up (6.4+2.9 versus 0.25+0.45, p<0.001). Both basal and residual LES pressures decreased significantly (28.2+14.1 mmHg versus 12.8+6.3 and 22.4+11.3 versus 6.3+3.4 mmHg, p=0.025 and <0.001, resp.). Barium column height at 5 minutes on TBE reduced from 6.8+4.9 cm to 2.3+2.9 cm (p=0.05). Two patients (10%) had mucosal perforations and one had delayed bleeding (5%). Conclusions. Two-person technique of POEM with combination of an advanced endoscopist and a thoracic surgeon is highly successful with low risk of complications.
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spelling doaj-art-2f4210955673449eb676bd10037f02ab2025-02-03T05:45:23ZengWileyCanadian Journal of Gastroenterology and Hepatology2291-27892291-27972016-01-01201610.1155/2016/26561012656101Two-Person Technique of Peroral Endoscopic Myotomy for Achalasia with an Advanced Endoscopist and a Thoracic Surgeon: Initial ExperienceMadhusudhan R. Sanaka0Ramprasad Jegadeesan1Prashanthi N. Thota2Udayakumar Navaneethan3Rocio Lopez4Sudish C. Murthy5Siva Raja6Department of Gastroenterology, Cleveland Clinic, Cleveland, OH 44195, USADepartment of Gastroenterology, Cleveland Clinic, Cleveland, OH 44195, USADepartment of Gastroenterology, Cleveland Clinic, Cleveland, OH 44195, USADepartment of Gastroenterology, Cleveland Clinic, Cleveland, OH 44195, USADepartment of Gastroenterology, Cleveland Clinic, Cleveland, OH 44195, USADepartment of Thoracic Surgery, Cleveland Clinic, Cleveland, OH 44195, USADepartment of Thoracic Surgery, Cleveland Clinic, Cleveland, OH 44195, USABackground and Aims. We initiated peroral endoscopic myotomy (POEM) utilizing a two-person technique with combination of an advanced endoscopist and a thoracic surgeon with complementary skills. Our aim was to determine the feasibility and outcomes in initial 20 patients. Methods. In this observational study, main outcomes measured were therapeutic success in relieving symptoms (Eckardt score < 3), decrease in lower esophageal sphincter (LES) pressures, improvement in emptying on timed barium esophagogram (TBE), and complications. Results. POEM was successful in all 20 patients with a mean operative time of 140.1+32.9 minutes. Eckardt symptom scores decreased significantly at two-month follow-up (6.4+2.9 versus 0.25+0.45, p<0.001). Both basal and residual LES pressures decreased significantly (28.2+14.1 mmHg versus 12.8+6.3 and 22.4+11.3 versus 6.3+3.4 mmHg, p=0.025 and <0.001, resp.). Barium column height at 5 minutes on TBE reduced from 6.8+4.9 cm to 2.3+2.9 cm (p=0.05). Two patients (10%) had mucosal perforations and one had delayed bleeding (5%). Conclusions. Two-person technique of POEM with combination of an advanced endoscopist and a thoracic surgeon is highly successful with low risk of complications.http://dx.doi.org/10.1155/2016/2656101
spellingShingle Madhusudhan R. Sanaka
Ramprasad Jegadeesan
Prashanthi N. Thota
Udayakumar Navaneethan
Rocio Lopez
Sudish C. Murthy
Siva Raja
Two-Person Technique of Peroral Endoscopic Myotomy for Achalasia with an Advanced Endoscopist and a Thoracic Surgeon: Initial Experience
Canadian Journal of Gastroenterology and Hepatology
title Two-Person Technique of Peroral Endoscopic Myotomy for Achalasia with an Advanced Endoscopist and a Thoracic Surgeon: Initial Experience
title_full Two-Person Technique of Peroral Endoscopic Myotomy for Achalasia with an Advanced Endoscopist and a Thoracic Surgeon: Initial Experience
title_fullStr Two-Person Technique of Peroral Endoscopic Myotomy for Achalasia with an Advanced Endoscopist and a Thoracic Surgeon: Initial Experience
title_full_unstemmed Two-Person Technique of Peroral Endoscopic Myotomy for Achalasia with an Advanced Endoscopist and a Thoracic Surgeon: Initial Experience
title_short Two-Person Technique of Peroral Endoscopic Myotomy for Achalasia with an Advanced Endoscopist and a Thoracic Surgeon: Initial Experience
title_sort two person technique of peroral endoscopic myotomy for achalasia with an advanced endoscopist and a thoracic surgeon initial experience
url http://dx.doi.org/10.1155/2016/2656101
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