A Leydig Cell Tumour in a Cat: Histological and Immunohistochemical Findings
A 13-year-old intact male cat was submitted to castration after the finding of the enlargement of the right testis during the clinical visit. Macroscopically, a nodule of 2 cm of diameter was observed on the cut surface of the enlarged testis. Histologically, the nodule was composed by polyhedral to...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Case Reports in Veterinary Medicine |
| Online Access: | http://dx.doi.org/10.1155/2013/670398 |
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| author | Pietro Asproni Francesca Millanta Davide Lorenzi Alessandro Poli |
| author_facet | Pietro Asproni Francesca Millanta Davide Lorenzi Alessandro Poli |
| author_sort | Pietro Asproni |
| collection | DOAJ |
| description | A 13-year-old intact male cat was submitted to castration after the finding of the enlargement of the right testis during the clinical visit. Macroscopically, a nodule of 2 cm of diameter was observed on the cut surface of the enlarged testis. Histologically, the nodule was composed by polyhedral to elongated cells with a large, eosinophilic, and vacuolated cytoplasm and small, round, and dark nuclei. These cells were arranged in acinar structures and solid sheets. The tumour was diagnosed as a Leydig cell tumour. Immunohistochemical analysis revealed that neoplastic cells were vimentin, calretinin, and melan-A positive, whereas a lack of immunoreactivity to cytokeratins confirmed the diagnosis. To our knowledge, this is the first description of a feline Leydig cells tumour without any concurrent testicular neoplasm or in a nonretained testis. |
| format | Article |
| id | doaj-art-2f17c567e2a742e3a578464251c03018 |
| institution | Kabale University |
| issn | 2090-7001 2090-701X |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Veterinary Medicine |
| spelling | doaj-art-2f17c567e2a742e3a578464251c030182025-02-03T06:06:03ZengWileyCase Reports in Veterinary Medicine2090-70012090-701X2013-01-01201310.1155/2013/670398670398A Leydig Cell Tumour in a Cat: Histological and Immunohistochemical FindingsPietro Asproni0Francesca Millanta1Davide Lorenzi2Alessandro Poli3Department of Veterinary Sciences, University of Pisa, Viale delle Piagge, 2, 56124 Pisa, ItalyDepartment of Veterinary Sciences, University of Pisa, Viale delle Piagge, 2, 56124 Pisa, ItalyDepartment of Veterinary Sciences, University of Pisa, Viale delle Piagge, 2, 56124 Pisa, ItalyDepartment of Veterinary Sciences, University of Pisa, Viale delle Piagge, 2, 56124 Pisa, ItalyA 13-year-old intact male cat was submitted to castration after the finding of the enlargement of the right testis during the clinical visit. Macroscopically, a nodule of 2 cm of diameter was observed on the cut surface of the enlarged testis. Histologically, the nodule was composed by polyhedral to elongated cells with a large, eosinophilic, and vacuolated cytoplasm and small, round, and dark nuclei. These cells were arranged in acinar structures and solid sheets. The tumour was diagnosed as a Leydig cell tumour. Immunohistochemical analysis revealed that neoplastic cells were vimentin, calretinin, and melan-A positive, whereas a lack of immunoreactivity to cytokeratins confirmed the diagnosis. To our knowledge, this is the first description of a feline Leydig cells tumour without any concurrent testicular neoplasm or in a nonretained testis.http://dx.doi.org/10.1155/2013/670398 |
| spellingShingle | Pietro Asproni Francesca Millanta Davide Lorenzi Alessandro Poli A Leydig Cell Tumour in a Cat: Histological and Immunohistochemical Findings Case Reports in Veterinary Medicine |
| title | A Leydig Cell Tumour in a Cat: Histological and Immunohistochemical Findings |
| title_full | A Leydig Cell Tumour in a Cat: Histological and Immunohistochemical Findings |
| title_fullStr | A Leydig Cell Tumour in a Cat: Histological and Immunohistochemical Findings |
| title_full_unstemmed | A Leydig Cell Tumour in a Cat: Histological and Immunohistochemical Findings |
| title_short | A Leydig Cell Tumour in a Cat: Histological and Immunohistochemical Findings |
| title_sort | leydig cell tumour in a cat histological and immunohistochemical findings |
| url | http://dx.doi.org/10.1155/2013/670398 |
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