Emergence of transferable daptomycin resistance in Gram-positive bacteria

Emergence of transferable daptomycin resistance in Gram-positive bacteria

Abstract Daptomycin (DAP) is a last-resort antibiotic to treat infections by multiresistant Gram-positive pathogens, including methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci. DAP resistance and clinical treatment failure has been associated with adaptive chro...

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Main Authors: Tessa Marciniak, Lukas Kirchner, Silver A. Wolf, Birgit Walther, Thorsten Bischler, Justin Nyasinga, Revathi Gunturu, Torsten Semmler, Tom Gräfenhan, Andrew Whitelaw, Oliver Scherf-Clavel, Ulrike Holzgrabe, Wilma Ziebuhr
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:npj Antimicrobials and Resistance
Online Access:https://doi.org/10.1038/s44259-025-00109-z
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