Mushroom β-glucan and polyphenol formulations as natural immunity boosters and balancers: nature of the application
Mushrooms are experiencing a kind of renaissance as a part of the contemporary human diet. These valuable organisms are more than food, they fit in perfectly as a novel market group known as nutra-mycoceuticals. Immune-balancing mushroom dietary fibers and secondary metabolites such as polyphenols a...
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| Format: | Article |
| Language: | English |
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Tsinghua University Press
2023-03-01
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| Series: | Food Science and Human Wellness |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213453022001525 |
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| author | Maja Kozarski Anita Klaus Leo van Griensven Dragica Jakovljevic Nina Todorovic Wan Abd Al Qadr Imad Wan-Mohtar Jovana Vunduk |
| author_facet | Maja Kozarski Anita Klaus Leo van Griensven Dragica Jakovljevic Nina Todorovic Wan Abd Al Qadr Imad Wan-Mohtar Jovana Vunduk |
| author_sort | Maja Kozarski |
| collection | DOAJ |
| description | Mushrooms are experiencing a kind of renaissance as a part of the contemporary human diet. These valuable organisms are more than food, they fit in perfectly as a novel market group known as nutra-mycoceuticals. Immune-balancing mushroom dietary fibers and secondary metabolites such as polyphenols are the main focus of the healthcare industry. Wellness and cosmetic companies are increasingly using mushroom extracts rich in these ingredients. This review considers the basic molecular immunomodulatory mechanisms of action of the most commonly used mushroom dietary fibers, β-glucans. The literature data on their bioavailability, metabolic transformations, preclinical and human clinical research, and safety are discussed. Immunomodulatory mechanisms of polyphenol ingredients are also considered. These molecules present great potential in the design of the new immunity balancer formulations according to their widespread structural diversity. Finally, we draw attention to the perspectives of modern trends in mushroom nutraceutical and cosmeceutical formulations to strengthen and balance immunity. |
| format | Article |
| id | doaj-art-2f1432b3d97541cba8513f5fdf7d6409 |
| institution | Kabale University |
| issn | 2213-4530 |
| language | English |
| publishDate | 2023-03-01 |
| publisher | Tsinghua University Press |
| record_format | Article |
| series | Food Science and Human Wellness |
| spelling | doaj-art-2f1432b3d97541cba8513f5fdf7d64092025-02-03T06:55:49ZengTsinghua University PressFood Science and Human Wellness2213-45302023-03-01122378396Mushroom β-glucan and polyphenol formulations as natural immunity boosters and balancers: nature of the applicationMaja Kozarski0Anita Klaus1Leo van Griensven2Dragica Jakovljevic3Nina Todorovic4Wan Abd Al Qadr Imad Wan-Mohtar5Jovana Vunduk6Institute of Food Technology and Biochemistry, Faculty of Agriculture, University of Belgrade, Belgrade 11080, Serbia; Corresponding author at: Institute of Food Technology and Biochemistry, Faculty of Agriculture, University of Belgrade, Belgrade 11080, Serbia.Institute of Food Technology and Biochemistry, Faculty of Agriculture, University of Belgrade, Belgrade 11080, SerbiaPlant Research International, Wageningen University and Research Centre, Wageningen 6700 AA, the NetherlandsInstitute of Chemistry, Technology and Metallurgy, University of Belgrade, Belgrade 11000, SerbiaInstitute of Chemistry, Technology and Metallurgy, University of Belgrade, Belgrade 11000, SerbiaFunctional Omics and Bioprocess Development Laboratory, Institute of Biological Sciences, Faculty of Science, Universiti Malaya, Kuala Lumpur 50603, MalaysiaInstitute of General and Physical Chemistry, University of Belgrade, Belgrade 11158, SerbiaMushrooms are experiencing a kind of renaissance as a part of the contemporary human diet. These valuable organisms are more than food, they fit in perfectly as a novel market group known as nutra-mycoceuticals. Immune-balancing mushroom dietary fibers and secondary metabolites such as polyphenols are the main focus of the healthcare industry. Wellness and cosmetic companies are increasingly using mushroom extracts rich in these ingredients. This review considers the basic molecular immunomodulatory mechanisms of action of the most commonly used mushroom dietary fibers, β-glucans. The literature data on their bioavailability, metabolic transformations, preclinical and human clinical research, and safety are discussed. Immunomodulatory mechanisms of polyphenol ingredients are also considered. These molecules present great potential in the design of the new immunity balancer formulations according to their widespread structural diversity. Finally, we draw attention to the perspectives of modern trends in mushroom nutraceutical and cosmeceutical formulations to strengthen and balance immunity.http://www.sciencedirect.com/science/article/pii/S2213453022001525Mushroomsβ-GlucanPolyphenolsImmunity boosters;SuperfoodNatural cosmetics |
| spellingShingle | Maja Kozarski Anita Klaus Leo van Griensven Dragica Jakovljevic Nina Todorovic Wan Abd Al Qadr Imad Wan-Mohtar Jovana Vunduk Mushroom β-glucan and polyphenol formulations as natural immunity boosters and balancers: nature of the application Food Science and Human Wellness Mushrooms β-Glucan Polyphenols Immunity boosters; Superfood Natural cosmetics |
| title | Mushroom β-glucan and polyphenol formulations as natural immunity boosters and balancers: nature of the application |
| title_full | Mushroom β-glucan and polyphenol formulations as natural immunity boosters and balancers: nature of the application |
| title_fullStr | Mushroom β-glucan and polyphenol formulations as natural immunity boosters and balancers: nature of the application |
| title_full_unstemmed | Mushroom β-glucan and polyphenol formulations as natural immunity boosters and balancers: nature of the application |
| title_short | Mushroom β-glucan and polyphenol formulations as natural immunity boosters and balancers: nature of the application |
| title_sort | mushroom β glucan and polyphenol formulations as natural immunity boosters and balancers nature of the application |
| topic | Mushrooms β-Glucan Polyphenols Immunity boosters; Superfood Natural cosmetics |
| url | http://www.sciencedirect.com/science/article/pii/S2213453022001525 |
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