Evidence for divergent endocrine regulation of the murine and ovine GnRH receptor gene promoters

Evidence for divergent endocrine regulation of the murine and ovine GnRH receptor gene promoters

Activin, GnRH, and estrogen are key endocrine inputs known to regulate the GnRH receptor (GnRHR) promoter; however, it has become increasingly evident that the mechanisms regulating the GnRHR promoter vary by model and species. To explore these differences, transgenic mice harboring either a wild-ty...

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Bibliographic Details
Main Authors: Christianne Magee, Jennifer E. Kouri, Brian D. Cherrington, Jeremy D. Cantlon, Dilyara A. Murtazina, Todd A. Farmerie, Meredith H. Davidsen, Terry M. Nett, Colin M. Clay
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Endocrinology
Subjects:
GnRH receptor
activin
estrogen gene expression
transgenic mice
follistatin
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2025.1597028/full
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https://www.frontiersin.org/articles/10.3389/fendo.2025.1597028/full

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