Granular Cell Tumor of Breast – A Rare Case Report

Granular cell tumours are low-grade tumours originating from Schwann cells of peripheral nerves. This is a case of 38-year-old female who presented with a lump in breast. Radiologically, it was classified as malignant. A wide local excision was performed and the specimen was received for frozen sec...

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Main Authors: Agam Hans, Parneet Kaur, Deepika Puar, Neha Singh, Maitrayee Roy, Ritika Nidhi
Format: Article
Language:English
Published: Dr. Annil Mahajan 2025-07-01
Series:JK Science
Subjects:
Online Access:https://journal.jkscience.org/index.php/JK-Science/article/view/382
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author Agam Hans
Parneet Kaur
Deepika Puar
Neha Singh
Maitrayee Roy
Ritika Nidhi
author_facet Agam Hans
Parneet Kaur
Deepika Puar
Neha Singh
Maitrayee Roy
Ritika Nidhi
author_sort Agam Hans
collection DOAJ
description Granular cell tumours are low-grade tumours originating from Schwann cells of peripheral nerves. This is a case of 38-year-old female who presented with a lump in breast. Radiologically, it was classified as malignant. A wide local excision was performed and the specimen was received for frozen section evaluation which revealed a nodular firm mass with grey white to tan yellow, finely granular texture on cut section. Microscopic sections revealed tumor cells to be polygonal to spindle shaped with small to medium sized nuclei and abundant eosinophilic granular cytoplasm. Tumor cells were S100 and CD68 positive. The final diagnosis was rendered as granular cell tumour.
format Article
id doaj-art-2ec0a07df11b48158b3611ce99856477
institution OA Journals
issn 0972-1177
language English
publishDate 2025-07-01
publisher Dr. Annil Mahajan
record_format Article
series JK Science
spelling doaj-art-2ec0a07df11b48158b3611ce998564772025-08-20T02:39:03ZengDr. Annil MahajanJK Science0972-11772025-07-01273Granular Cell Tumor of Breast – A Rare Case ReportAgam HansParneet KaurDeepika PuarNeha SinghMaitrayee RoyRitika Nidhi Granular cell tumours are low-grade tumours originating from Schwann cells of peripheral nerves. This is a case of 38-year-old female who presented with a lump in breast. Radiologically, it was classified as malignant. A wide local excision was performed and the specimen was received for frozen section evaluation which revealed a nodular firm mass with grey white to tan yellow, finely granular texture on cut section. Microscopic sections revealed tumor cells to be polygonal to spindle shaped with small to medium sized nuclei and abundant eosinophilic granular cytoplasm. Tumor cells were S100 and CD68 positive. The final diagnosis was rendered as granular cell tumour. https://journal.jkscience.org/index.php/JK-Science/article/view/382Frozen SectionSchwann CellsAbrikossoff’s Tumour
spellingShingle Agam Hans
Parneet Kaur
Deepika Puar
Neha Singh
Maitrayee Roy
Ritika Nidhi
Granular Cell Tumor of Breast – A Rare Case Report
JK Science
Frozen Section
Schwann Cells
Abrikossoff’s Tumour
title Granular Cell Tumor of Breast – A Rare Case Report
title_full Granular Cell Tumor of Breast – A Rare Case Report
title_fullStr Granular Cell Tumor of Breast – A Rare Case Report
title_full_unstemmed Granular Cell Tumor of Breast – A Rare Case Report
title_short Granular Cell Tumor of Breast – A Rare Case Report
title_sort granular cell tumor of breast a rare case report
topic Frozen Section
Schwann Cells
Abrikossoff’s Tumour
url https://journal.jkscience.org/index.php/JK-Science/article/view/382
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AT parneetkaur granularcelltumorofbreastararecasereport
AT deepikapuar granularcelltumorofbreastararecasereport
AT nehasingh granularcelltumorofbreastararecasereport
AT maitrayeeroy granularcelltumorofbreastararecasereport
AT ritikanidhi granularcelltumorofbreastararecasereport