Illumina complete long read assay yields contiguous bacterial genomes from human gut metagenomes

Illumina complete long read assay yields contiguous bacterial genomes from human gut metagenomes

ABSTRACT Metagenomics enables direct investigation of the gene content and potential functions of gut bacteria without isolation and culture. However, metagenome-assembled genomes are often incomplete and have low contiguity due to challenges in assembling repeated genomic elements. Long-read sequen...

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Bibliographic Details
Main Authors: Dylan G. Maghini, Yuya Kiguchi, Aaron E. Darling, Leigh G. Monahan, Aaron L. Halpern, Catherine M. Burke, Erich Jaeger, Aaron Statham, Tiffany Truong, Kevin Ying, Stephen P. Bruinsma, Gary P. Schroth, Ami S. Bhatt
Format: Article
Language:English
Published: American Society for Microbiology 2025-08-01
Series:mSystems
Subjects:
metagenomics
sequencing
microbiome
genomics
Online Access:https://journals.asm.org/doi/10.1128/msystems.01531-24
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