Overexpression of KMT9α is associated with poor outcome in cholangiocarcinoma patients

Overexpression of KMT9α is associated with poor outcome in cholangiocarcinoma patients

Abstract Purpose The newly discovered histone methyltransferase KMT9 serves as an epigenetic regulator of carcinogenesis in various cancer entities. For the first time, we investigated the presence of KMT9α in cholangiocarcinoma, the association with histologic subtypes, and its impact on survival....

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Main Authors: Maximilian N. Kinzler, Eric Metzger, Rebecca Schulz, Katrin Bankov, Anna Ramos-Triguero, Falko Schulze, Steffen Gretser, Nada Abedin, Armin Wiegering, Stefan Zeuzem, Dirk Walter, Henning Reis, Roland Schüle, Peter J. Wild
Format: Article
Language:English
Published: Springer 2025-05-01
Series:Journal of Cancer Research and Clinical Oncology
Subjects:
Biomarker
Cholangiocarcinoma
Surgical oncology
Lysine methyltransferase 9
KMT9α
Online Access:https://doi.org/10.1007/s00432-025-06214-w
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https://doi.org/10.1007/s00432-025-06214-w

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