Noninvasive molecular imaging using anti-Trop-2 aptamer for targeted therapy of small cell lung cancer

Noninvasive molecular imaging using anti-Trop-2 aptamer for targeted therapy of small cell lung cancer

Abstract Recent advancements in antibody-drug conjugates (ADCs) targeting trophoblast surface cell antigen 2 (Trop-2) have brought important progress in the field of targeted therapy. This progress also holds promise for the treatment of small cell lung cancer (SCLC) as anti-Trop-2 therapy appears t...

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Bibliographic Details
Main Authors: Yamei Chen, Xuwei Liu, Yang Sun, Keying Liu, Ding Ding, Shaoli Song, Weihong Tan
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Journal of Nanobiotechnology
Subjects:
Small cell lung cancer
Trop-2
Aptamer
Molecular imaging
Antibody-drug conjugates
Online Access:https://doi.org/10.1186/s12951-025-03184-6
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