Rack1 promotes breast cancer stemness properties and tumorigenesis through the E2F1-SOX2 axis

Abstract Background Breast cancer remains the most prevalent malignancy and the leading cause of cancer-related mortality among women worldwide. The primary factors contributing to the deterioration and death of patients with breast cancer are metastasis, recurrence, and drug resistance. These pheno...

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Bibliographic Details
Main Authors: Yidi Jia, Luoming Zhang, Wei Zhou, Shuhua Chen, He Zhang, Liming Liu, Hui Guo, Zhiyong Wang, Yanfen Cui, Ruifang Niu, Fei Zhang
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Cancer Cell International
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Online Access:https://doi.org/10.1186/s12935-025-03678-1
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