Human T-cell leukemia virus type 1: oncogenic potential and vaccine development strategies

Human T-cell leukemia virus type 1: oncogenic potential and vaccine development strategies

The human T-cell lymphotropic virus type 1 (HTLV-1) is a highly oncogenic retrovirus recognized as the causative agent of adult T-cell leukemia/lymphoma (ATLL) and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). Among the key risk factors for ATLL development are high proviral l...

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Main Authors: Jorge Vasconez-Gonzalez, Isaac A. Suárez-Sangucho, Esteban Acosta-Muñoz, Luis Paz y Miño, Domenic Borja-Mendoza, John Altamirano Alexander-Castillo, Julia Saa, Natasha Salazar-Calvopiña, Paúl Cárdenas, Andrés López-Cortés, Esteban Ortiz-Prado
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
HTLV-1
human T-cell leukemia virus type 1
oncogenesis
viral oncogenes
immune evasion
retrovirus
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2025.1587802/full
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https://www.frontiersin.org/articles/10.3389/fcimb.2025.1587802/full

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