Single nucleotide polymorphisms with cis-regulatory effects on long non-coding transcripts in human primary monocytes.

Single nucleotide polymorphisms with cis-regulatory effects on long non-coding transcripts in human primary monocytes.

We applied genome-wide allele-specific expression analysis of monocytes from 188 samples. Monocytes were purified from white blood cells of healthy blood donors to detect cis-acting genetic variation that regulates the expression of long non-coding RNAs. We analysed 8929 regions harboring genes for...

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Main Authors: Jonas Carlsson Almlöf, Per Lundmark, Anders Lundmark, Bing Ge, Tomi Pastinen, Cardiogenics Consortium, Alison H Goodall, François Cambien, Panos Deloukas, Willem H Ouwehand, Ann-Christine Syvänen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0102612
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