Effects of multiples hormones on intraocular pressure: A narrative review
This research examines the effects of hormones on intraocular pressure (IOP), focusing specifically on estrogen, progesterone, testosterone, oxytocin, thyroid hormones, melatonin, aldosterone, dopamine, growth hormone (GH), and insulin-like growth factor-1 (IGF-1). The literature indicated that GH,...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2025-01-01
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| Series: | Journal of Clinical Ophthalmology and Research |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/jcor.jcor_118_24 |
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| Summary: | This research examines the effects of hormones on intraocular pressure (IOP), focusing specifically on estrogen, progesterone, testosterone, oxytocin, thyroid hormones, melatonin, aldosterone, dopamine, growth hormone (GH), and insulin-like growth factor-1 (IGF-1). The literature indicated that GH, IGF-1, progesterone, melatonin, testosterone, oxytocin, and estrogen were associated with reduced IOP. However, the impact of estrogen on IOP may vary depending on the type (endogenous or exogenous estrogen), the stage of a woman’s life (premenopausal or postmenopausal), and the mode of administration (oral or nonoral). Although testosterone was found to reduce IOP, a significant association between high IOP and testosterone was found in female-to-male transgender individuals. The impact of dopamine on IOP also varied depending on the dopamine receptors. The study was conducted based on a literature review obtained from Google Scholar spanning from 1980 to 2023. All selected literature directly or indirectly explored the relationship between hormones and IOP in animals or humans. |
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| ISSN: | 2320-3897 2320-3900 |