Endometrioid Adenocarcinoma Metastatic to the Thyroid, Presenting Like Anaplastic Thyroid Cancer

Metastasis of uterine cancer to the head and neck is extremely rare. We report what we believe to be the first documented case of endometrioid adenocarcinoma metastasizing to the thyroid gland. An 80-year-old woman was referred to the otolaryngology service with a rapidly growing neck mass. The mass...

Full description

Saved in:
Bibliographic Details
Main Authors: Natasha Pollak, Gregory J. Renner, Ronald Miick, Shellaine R. Frazier
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Case Reports in Endocrinology
Online Access:http://dx.doi.org/10.1155/2011/246872
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832556051095879680
author Natasha Pollak
Gregory J. Renner
Ronald Miick
Shellaine R. Frazier
author_facet Natasha Pollak
Gregory J. Renner
Ronald Miick
Shellaine R. Frazier
author_sort Natasha Pollak
collection DOAJ
description Metastasis of uterine cancer to the head and neck is extremely rare. We report what we believe to be the first documented case of endometrioid adenocarcinoma metastasizing to the thyroid gland. An 80-year-old woman was referred to the otolaryngology service with a rapidly growing neck mass. The mass appeared to originate from the thyroid gland. Her clinical presentation was consistent with anaplastic thyroid carcinoma. A tracheostomy was performed. An open biopsy established the diagnosis of moderately differentiated adenocarcinoma, consistent with a gynecologic primary. The patient had undergone a hysterectomy 5 years prior for endometrioid adenocarcinoma. The thyroid tumor histology and immunophenotype corresponded well with her prior endometrial carcinoma, indicating that the thyroid mass was a metastasis from the endometrial primary. Radiotherapy appears to offer good local disease control in this rare case of endometrioid adenocarcinoma metastatic to the thyroid.
format Article
id doaj-art-2e7fe62c1483427ab5f2ecbc38c33053
institution Kabale University
issn 2090-6501
2090-651X
language English
publishDate 2011-01-01
publisher Wiley
record_format Article
series Case Reports in Endocrinology
spelling doaj-art-2e7fe62c1483427ab5f2ecbc38c330532025-02-03T05:46:23ZengWileyCase Reports in Endocrinology2090-65012090-651X2011-01-01201110.1155/2011/246872246872Endometrioid Adenocarcinoma Metastatic to the Thyroid, Presenting Like Anaplastic Thyroid CancerNatasha Pollak0Gregory J. Renner1Ronald Miick2Shellaine R. Frazier3Department of Otolaryngology-Head and Neck Surgery, Temple University School of Medicine, Kresge West, 3rd floor, 3400 North Broad Street, Philadelphia, PA 19140, USADepartment of Otolaryngology-Head and Neck Surgery, University of Missouri-Columbia, Columbia, MO 65212, USADepartment of Pathology and Laboratory Medicine, Albert Einstein Medical Center, Philadelphia, PA 19141, USADepartment of Pathology and Anatomical Sciences, University of Missouri-Columbia, Columbia, MO 65212, USAMetastasis of uterine cancer to the head and neck is extremely rare. We report what we believe to be the first documented case of endometrioid adenocarcinoma metastasizing to the thyroid gland. An 80-year-old woman was referred to the otolaryngology service with a rapidly growing neck mass. The mass appeared to originate from the thyroid gland. Her clinical presentation was consistent with anaplastic thyroid carcinoma. A tracheostomy was performed. An open biopsy established the diagnosis of moderately differentiated adenocarcinoma, consistent with a gynecologic primary. The patient had undergone a hysterectomy 5 years prior for endometrioid adenocarcinoma. The thyroid tumor histology and immunophenotype corresponded well with her prior endometrial carcinoma, indicating that the thyroid mass was a metastasis from the endometrial primary. Radiotherapy appears to offer good local disease control in this rare case of endometrioid adenocarcinoma metastatic to the thyroid.http://dx.doi.org/10.1155/2011/246872
spellingShingle Natasha Pollak
Gregory J. Renner
Ronald Miick
Shellaine R. Frazier
Endometrioid Adenocarcinoma Metastatic to the Thyroid, Presenting Like Anaplastic Thyroid Cancer
Case Reports in Endocrinology
title Endometrioid Adenocarcinoma Metastatic to the Thyroid, Presenting Like Anaplastic Thyroid Cancer
title_full Endometrioid Adenocarcinoma Metastatic to the Thyroid, Presenting Like Anaplastic Thyroid Cancer
title_fullStr Endometrioid Adenocarcinoma Metastatic to the Thyroid, Presenting Like Anaplastic Thyroid Cancer
title_full_unstemmed Endometrioid Adenocarcinoma Metastatic to the Thyroid, Presenting Like Anaplastic Thyroid Cancer
title_short Endometrioid Adenocarcinoma Metastatic to the Thyroid, Presenting Like Anaplastic Thyroid Cancer
title_sort endometrioid adenocarcinoma metastatic to the thyroid presenting like anaplastic thyroid cancer
url http://dx.doi.org/10.1155/2011/246872
work_keys_str_mv AT natashapollak endometrioidadenocarcinomametastatictothethyroidpresentinglikeanaplasticthyroidcancer
AT gregoryjrenner endometrioidadenocarcinomametastatictothethyroidpresentinglikeanaplasticthyroidcancer
AT ronaldmiick endometrioidadenocarcinomametastatictothethyroidpresentinglikeanaplasticthyroidcancer
AT shellainerfrazier endometrioidadenocarcinomametastatictothethyroidpresentinglikeanaplasticthyroidcancer