Engineering a 3D wounded skin equivalent to study early inflammatory and regenerative responses in vitro

IntroductionTraditional models for studying wound healing, including 2D cell cultures and animal models, present substantial limitations in mimicking human skin physiology. In this study, we present a three-dimensional wounded skin equivalent (3DWoundSE) composed of human cells as a physiologically...

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Bibliographic Details
Main Authors: Rima Nuwayhid, Nguyen Ngoc-Huyen, Dmitry Notov, Stefan Langer, Olga Kurow
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Bioengineering and Biotechnology
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Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2025.1621566/full
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