Optogenetic stimulation of inferior colliculus neurons elicits mesencephalic locomotor region activity and reverses haloperidol-induced catalepsy in rats

Optogenetic stimulation of inferior colliculus neurons elicits mesencephalic locomotor region activity and reverses haloperidol-induced catalepsy in rats

Abstract The inferior colliculus (IC) represents a pivotal midbrain area involved in processing sensory/emotional facets of auditory stimuli, potentially influencing motor responses. Our prior investigations showed that electric or chemical stimulation of the IC ameliorates haloperidol-induced catal...

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Bibliographic Details
Main Authors: José A. Pochapski, Jan Franke, Wolfgang Kruse, Ralf Jacob, Stefan Herlitze, Claudio Da Cunha, Rainer K. W. Schwarting, Liana Melo-Thomas
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Paradoxical kinesia
Inferior colliculus
Mesencephalic locomotor region
Catalepsy
Parkinson’s disease
Online Access:https://doi.org/10.1038/s41598-025-96995-4
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