Intima-media thickness and large artery elasticity in patients with ischemic chronic heart failure
Aim. To assess intima-media thickness (IMT) of carotid arteries (CA), large artery elasticity, and their effects on clinical prognosis in patients with ischemic chronic heart failure (CHF). Material and methods. The study included 207 patients (mean age 55,1±6,4 years) after myocardial infarction (M...
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| Format: | Article |
| Language: | Russian |
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«SILICEA-POLIGRAF» LLC
1970-01-01
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| Series: | Кардиоваскулярная терапия и профилактика |
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| Online Access: | https://cardiovascular.elpub.ru/jour/article/view/1993 |
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| author | N. A. Kosheleva A. P. Rebrov O. V. Karpova T. V. Martynova |
| author_facet | N. A. Kosheleva A. P. Rebrov O. V. Karpova T. V. Martynova |
| author_sort | N. A. Kosheleva |
| collection | DOAJ |
| description | Aim. To assess intima-media thickness (IMT) of carotid arteries (CA), large artery elasticity, and their effects on clinical prognosis in patients with ischemic chronic heart failure (CHF). Material and methods. The study included 207 patients (mean age 55,1±6,4 years) after myocardial infarction (MI), with CHF symptoms, and 40 healthy controls. The assessment of CA IMT was performed with Acuson 128 XP/10 device; large artery elasticity and stiffness was assessed with arteriograph TensioClinic (TensioMed, Hungary). Results. In CHF patients, increased CA IMT, increased large artery stiffness, and an association between aortic pulse wave velocity (APWV) and CA IMT were observed. APWV values >12 m/s were associated with a significantly higher risk of CHF decompensation (р=0,001), repeat MI (р=0,01), death (р=0,001), and all major cardiovascular events (CVE) (р=0,01), compared to APWV ≤12 m/s. Multivariate analysis results demonstrated that in CHF patients with APWV >12 m/s, one-year risk of CVE was 2,02 times higher than in patients with APWV ≤12 m/s (hazard ratio 2,02; 95 % CI 1,01-4,03). Conclusion. CA IMT was associated with APWV, while the latter was an independent risk factor of CVE in patients with ischemic CHF. |
| format | Article |
| id | doaj-art-2e2b24cd18a64d6ab5b702a707b9d7c0 |
| institution | DOAJ |
| issn | 1728-8800 2619-0125 |
| language | Russian |
| publishDate | 1970-01-01 |
| publisher | «SILICEA-POLIGRAF» LLC |
| record_format | Article |
| series | Кардиоваскулярная терапия и профилактика |
| spelling | doaj-art-2e2b24cd18a64d6ab5b702a707b9d7c02025-08-20T02:55:46Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01251970-01-0110739441705Intima-media thickness and large artery elasticity in patients with ischemic chronic heart failureN. A. Kosheleva0A. P. Rebrov1O. V. Karpova2T. V. Martynova3V.I. Razumovskyi Saratov State Medical UniversityV.I. Razumovskyi Saratov State Medical UniversitySaratov Region Clinical HospitalSaratov Region Clinical HospitalAim. To assess intima-media thickness (IMT) of carotid arteries (CA), large artery elasticity, and their effects on clinical prognosis in patients with ischemic chronic heart failure (CHF). Material and methods. The study included 207 patients (mean age 55,1±6,4 years) after myocardial infarction (MI), with CHF symptoms, and 40 healthy controls. The assessment of CA IMT was performed with Acuson 128 XP/10 device; large artery elasticity and stiffness was assessed with arteriograph TensioClinic (TensioMed, Hungary). Results. In CHF patients, increased CA IMT, increased large artery stiffness, and an association between aortic pulse wave velocity (APWV) and CA IMT were observed. APWV values >12 m/s were associated with a significantly higher risk of CHF decompensation (р=0,001), repeat MI (р=0,01), death (р=0,001), and all major cardiovascular events (CVE) (р=0,01), compared to APWV ≤12 m/s. Multivariate analysis results demonstrated that in CHF patients with APWV >12 m/s, one-year risk of CVE was 2,02 times higher than in patients with APWV ≤12 m/s (hazard ratio 2,02; 95 % CI 1,01-4,03). Conclusion. CA IMT was associated with APWV, while the latter was an independent risk factor of CVE in patients with ischemic CHF.https://cardiovascular.elpub.ru/jour/article/view/1993chronic heart failurecarotid artery intima-media thicknesslarge artery elasticityprognosis |
| spellingShingle | N. A. Kosheleva A. P. Rebrov O. V. Karpova T. V. Martynova Intima-media thickness and large artery elasticity in patients with ischemic chronic heart failure Кардиоваскулярная терапия и профилактика chronic heart failure carotid artery intima-media thickness large artery elasticity prognosis |
| title | Intima-media thickness and large artery elasticity in patients with ischemic chronic heart failure |
| title_full | Intima-media thickness and large artery elasticity in patients with ischemic chronic heart failure |
| title_fullStr | Intima-media thickness and large artery elasticity in patients with ischemic chronic heart failure |
| title_full_unstemmed | Intima-media thickness and large artery elasticity in patients with ischemic chronic heart failure |
| title_short | Intima-media thickness and large artery elasticity in patients with ischemic chronic heart failure |
| title_sort | intima media thickness and large artery elasticity in patients with ischemic chronic heart failure |
| topic | chronic heart failure carotid artery intima-media thickness large artery elasticity prognosis |
| url | https://cardiovascular.elpub.ru/jour/article/view/1993 |
| work_keys_str_mv | AT nakosheleva intimamediathicknessandlargearteryelasticityinpatientswithischemicchronicheartfailure AT aprebrov intimamediathicknessandlargearteryelasticityinpatientswithischemicchronicheartfailure AT ovkarpova intimamediathicknessandlargearteryelasticityinpatientswithischemicchronicheartfailure AT tvmartynova intimamediathicknessandlargearteryelasticityinpatientswithischemicchronicheartfailure |