Targeting fungal lipid synthesis for antifungal drug development and potentiation of contemporary antifungals
Abstract Two of the three most commonly used classes of antifungal drugs target the fungal membrane through perturbation of sterol biosynthesis or function. In addition to these triazole and polyene antifungals, recent research is identifying new antifungal molecules that perturb lipid biosynthesis...
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| Main Authors: | Cecilia Gutierrez-Perez, Robert A. Cramer |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-04-01
|
| Series: | npj Antimicrobials and Resistance |
| Online Access: | https://doi.org/10.1038/s44259-025-00093-4 |
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