Custom-Made Computer-Aided-Design/Computer-Aided-Manufacturing Biphasic Calcium-Phosphate Scaffold for Augmentation of an Atrophic Mandibular Anterior Ridge
This report documents the clinical, radiographic, and histologic outcome of a custom-made computer-aided-design/computer-aided-manufactured (CAD/CAM) scaffold used for the alveolar ridge augmentation of a severely atrophic anterior mandible. Computed tomographic (CT) images of an atrophic anterior m...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Case Reports in Dentistry |
| Online Access: | http://dx.doi.org/10.1155/2015/941265 |
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| author | Francesco Guido Mangano Piero Antonio Zecca Ric van Noort Samvel Apresyan Giovanna Iezzi Adriano Piattelli Aldo Macchi Carlo Mangano |
| author_facet | Francesco Guido Mangano Piero Antonio Zecca Ric van Noort Samvel Apresyan Giovanna Iezzi Adriano Piattelli Aldo Macchi Carlo Mangano |
| author_sort | Francesco Guido Mangano |
| collection | DOAJ |
| description | This report documents the clinical, radiographic, and histologic outcome of a custom-made computer-aided-design/computer-aided-manufactured (CAD/CAM) scaffold used for the alveolar ridge augmentation of a severely atrophic anterior mandible. Computed tomographic (CT) images of an atrophic anterior mandible were acquired and modified into a 3-dimensional (3D) reconstruction model; this was transferred to a CAD program, where a custom-made scaffold was designed. CAM software generated a set of tool-paths for the manufacture of the scaffold on a computer-numerical-control milling machine into the exact shape of the 3D design. A custom-made scaffold was milled from a synthetic micromacroporous biphasic calcium phosphate (BCP) block. The scaffold closely matched the shape of the defect: this helped to reduce the time for the surgery and contributed to good healing. One year later, newly formed and well-integrated bone was clinically available, and two implants (AnyRidge, MegaGen, Gyeongbuk, South Korea) were placed. The histologic samples retrieved from the implant sites revealed compact mature bone undergoing remodelling, marrow spaces, and newly formed trabecular bone surrounded by residual BCP particles. This study demonstrates that custom-made scaffolds can be fabricated by combining CT scans and CAD/CAM techniques. Further studies on a larger sample of patients are needed to confirm these results. |
| format | Article |
| id | doaj-art-2ddf2bb5b0d5465796cb4b0e6e803e70 |
| institution | Kabale University |
| issn | 2090-6447 2090-6455 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Dentistry |
| spelling | doaj-art-2ddf2bb5b0d5465796cb4b0e6e803e702025-02-03T05:45:45ZengWileyCase Reports in Dentistry2090-64472090-64552015-01-01201510.1155/2015/941265941265Custom-Made Computer-Aided-Design/Computer-Aided-Manufacturing Biphasic Calcium-Phosphate Scaffold for Augmentation of an Atrophic Mandibular Anterior RidgeFrancesco Guido Mangano0Piero Antonio Zecca1Ric van Noort2Samvel Apresyan3Giovanna Iezzi4Adriano Piattelli5Aldo Macchi6Carlo Mangano7Department of Surgical and Morphological Science, Dental School, University of Insubria, Via Giuseppe Piatti 10, 21100 Varese, ItalyDepartment of Surgical and Morphological Science, Dental School, University of Insubria, Via Giuseppe Piatti 10, 21100 Varese, ItalyAcademic Unit of Restorative Dentistry, School of Clinical Dentistry, University of Sheffield, 19 Claremont Crescent, Sheffield S10 2TA, UKAcademic Unit of Prosthodontics, Moscow State University of Medicine and Dentistry, 20 Delegatskaya Street, Moscow 127473, RussiaDepartment of Medical, Oral and Biotechnological Sciences, Dental School, G. d’Annunzio University, Via dei Vestini 31, 66100 Chieti, ItalyDepartment of Medical, Oral and Biotechnological Sciences, Dental School, G. d’Annunzio University, Via dei Vestini 31, 66100 Chieti, ItalyDepartment of Surgical and Morphological Science, Dental School, University of Insubria, Via Giuseppe Piatti 10, 21100 Varese, ItalyDepartment of Surgical and Morphological Science, Dental School, University of Insubria, Via Giuseppe Piatti 10, 21100 Varese, ItalyThis report documents the clinical, radiographic, and histologic outcome of a custom-made computer-aided-design/computer-aided-manufactured (CAD/CAM) scaffold used for the alveolar ridge augmentation of a severely atrophic anterior mandible. Computed tomographic (CT) images of an atrophic anterior mandible were acquired and modified into a 3-dimensional (3D) reconstruction model; this was transferred to a CAD program, where a custom-made scaffold was designed. CAM software generated a set of tool-paths for the manufacture of the scaffold on a computer-numerical-control milling machine into the exact shape of the 3D design. A custom-made scaffold was milled from a synthetic micromacroporous biphasic calcium phosphate (BCP) block. The scaffold closely matched the shape of the defect: this helped to reduce the time for the surgery and contributed to good healing. One year later, newly formed and well-integrated bone was clinically available, and two implants (AnyRidge, MegaGen, Gyeongbuk, South Korea) were placed. The histologic samples retrieved from the implant sites revealed compact mature bone undergoing remodelling, marrow spaces, and newly formed trabecular bone surrounded by residual BCP particles. This study demonstrates that custom-made scaffolds can be fabricated by combining CT scans and CAD/CAM techniques. Further studies on a larger sample of patients are needed to confirm these results.http://dx.doi.org/10.1155/2015/941265 |
| spellingShingle | Francesco Guido Mangano Piero Antonio Zecca Ric van Noort Samvel Apresyan Giovanna Iezzi Adriano Piattelli Aldo Macchi Carlo Mangano Custom-Made Computer-Aided-Design/Computer-Aided-Manufacturing Biphasic Calcium-Phosphate Scaffold for Augmentation of an Atrophic Mandibular Anterior Ridge Case Reports in Dentistry |
| title | Custom-Made Computer-Aided-Design/Computer-Aided-Manufacturing Biphasic Calcium-Phosphate Scaffold for Augmentation of an Atrophic Mandibular Anterior Ridge |
| title_full | Custom-Made Computer-Aided-Design/Computer-Aided-Manufacturing Biphasic Calcium-Phosphate Scaffold for Augmentation of an Atrophic Mandibular Anterior Ridge |
| title_fullStr | Custom-Made Computer-Aided-Design/Computer-Aided-Manufacturing Biphasic Calcium-Phosphate Scaffold for Augmentation of an Atrophic Mandibular Anterior Ridge |
| title_full_unstemmed | Custom-Made Computer-Aided-Design/Computer-Aided-Manufacturing Biphasic Calcium-Phosphate Scaffold for Augmentation of an Atrophic Mandibular Anterior Ridge |
| title_short | Custom-Made Computer-Aided-Design/Computer-Aided-Manufacturing Biphasic Calcium-Phosphate Scaffold for Augmentation of an Atrophic Mandibular Anterior Ridge |
| title_sort | custom made computer aided design computer aided manufacturing biphasic calcium phosphate scaffold for augmentation of an atrophic mandibular anterior ridge |
| url | http://dx.doi.org/10.1155/2015/941265 |
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