Validity of patient-derived xenograft mouse models for lung cancer based on exome sequencing data
Patient-derived xenograft (PDX) mouse models are frequently used to test the drug efficacy in diverse types of cancer. They are known to recapitulate the patient characteristics faithfully, but a systematic survey with a large number of cases is yet missing in lung cancer. Here we report the compari...
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Main Authors: | Jaewon Kim, Hwanseok Rhee, Jhingook Kim, Sanghyuk Lee |
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Format: | Article |
Language: | English |
Published: |
BioMed Central
2020-03-01
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Series: | Genomics & Informatics |
Subjects: | |
Online Access: | http://genominfo.org/upload/pdf/gi-2020-18-1-e3.pdf |
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